Recent findings of green tea extract AR25 (Exolise) and its activity for the treatment of obesity

The green tea extract AR25 is an 80 % ethanolic dry extract standardized at 25 % catechins expressed as epigallocatechin gallate (EGCG). In vitro, green tea extract AR25 exerts a direct inhibition of gastric and pancreatic lipases and a stimulation of thermogenesis. In an open study, the effects of extract AR25 were evaluated in moderately obese patients. After 3 months, body weight was decreased by 4.6 % and waist circumference by 4.48 %. These results suggest the green tea extract AR25 to be a natural product for the treatment of obesity, which exerts its activity by several ways: inhibition of lipases and stimulation of thermogenesis.