4.6 Article

Operating characteristics and extensions of the false discovery rate procedure

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BLACKWELL PUBL LTD
DOI: 10.1111/1467-9868.00347

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false discovery rate; multiple testing; p-values; risk

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We investigate the operating characteristics of the Benjamini-Hochberg false discovery rate procedure for multiple testing. This is a distribution-free method that controls the expected fraction of falsely rejected null hypotheses among those rejected. The paper provides a framework for understanding more about this procedure. We first study the asymptotic properties of the 'deciding point' D that determines the critical p-value. From this, we obtain explicit asymptotic expressions for a particular risk function. We introduce the dual notion of false non-rejections and we consider a risk function that combines the false discovery rate and false non-rejections. We also consider the optimal procedure with respect to a measure of conditional risk.

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