期刊
JOURNAL OF DIABETES AND ITS COMPLICATIONS
卷 16, 期 1, 页码 50-55出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/S1056-8727(01)00190-8
关键词
insulin resistance; troglitazone; neointimal tissue proliferation; intravascular ultrasound; stent
Serial intravascular ultra-sound (IVUS) Studies in 55 nondiabetic patients showed that neointimal tissue proliferation after stent implantation in patients with impaired glucose tolerance (IGT) was greater than that in Patients with normal glucose tolerance at follow-up. Multiple regression analysis showed that the sum of insulin levels was the best index at follow-up, Another group of serial IVUS studies were performed in 62 stented lesions in 52 patients with Type 2 diabetes mellitus (DM). The study patients were randomized into a troglitazone group and a control group. The neointimal tissue proliferation at follow-up in the troglitazone group was significantly smaller than that in the control group. (C) 2002 Elsevier Science Inc. All rights reserved.
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