期刊
ARTHRITIS RESEARCH
卷 4, 期 6, 页码 346-352出版社
BIOMED CENTRAL LTD
DOI: 10.1186/ar598
关键词
IFN-beta; multiple sclerosis; rheumatoid arthritis
类别
IFN-beta treatment is emerging as a potentially effective form of therapy in various immune-mediated conditions. The present review addresses the possible role of IFN-beta in immune-mediated diseases such as multiple sclerosis and rheumatoid arthritis. Several placebo-controlled trials are discussed, as are the available immunological data that are relevant to this field. Review of these data provides evidence that IFN-beta has some beneficial therapeutic effect in patients with relapsing-remitting multiple sclerosis and might also have antirheumatic potential. This notion is supported by recent studies showing a critical role for IFN-beta in bone homeostasis.
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