期刊
CEPHALALGIA
卷 33, 期 16, 页码 1283-1291出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/0333102413493193
关键词
Chronic cluster headache; chronic migraine; occipital nerve stimulation (ONS); treatment costs; complications; outcome
Background Occipital nerve stimulation (ONS) has been shown to be effective for selected patients with intractable headache disorders. We performed a prospective critical evaluation of complications and direct treatment costs. Methods Twenty-seven patients with chronic cluster headache (CCH, n=24) or chronic migraine (CM, n=3) underwent a trial phase with bilateral ONS and subsequent implantation of a permanent generator (IPG), if responsive to treatment according to predefined criteria. Procedural and long-term complications as well as direct treatment costs of neuromodulation therapy of ONS were recorded over a mean follow-up period of 20 months (range 5-47 months). Results Twenty-five of 27 patients (93%) responded to treatment. Twenty-one complications in 14 patients were identified, necessitating reoperation in 13 cases. Overall treatment costs were Euro761,043, including hardware-related costs of Euro506,019, costs for primary hospital care of Euro210,496, and complications related to hospitalization costs of Euro44,528. This results in a per case-based cost of Euro9445 for hospitalization and Euro18,741 for hardware costs, totaling Euro28,186. Conclusion ONS for treatment of refractory CCH and CM is a cost-intensive treatment option with a significant complication rate. Nevertheless, patients with refractory primary headache disorders may experience substantial relief of pain attacks, and headache days, respectively.
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