期刊
CEPHALALGIA
卷 34, 期 3, 页码 219-223出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/0333102413505241
关键词
Parasomnia; DBS; cluster headache; trigeminal autonomic cephalalgias; REM behavioural disorder
资金
- Department of Health National Institute
- Sainsbury Monument Trust
- Parkinson's Appeal for Deep Brain Stimulation
Background Early observations by von Economo showed that the posterior part of the hypothalamus (PH) plays a prominent role in sleep-wake regulation. The PH is a candidate area involved in cluster headaches and other trigeminal autonomic cephalalgias (TACs) and is targeted for deep brain stimulation (DBS). Case reports Sleep studies in two men, 69- and 39-years-old, with pre-existing sleep disorders, before and after PH-DBS for pharamacoresistant cluster headache and SUNCT syndrome showed that PH-DBS led to a dramatic alteration of the patients' sleep patterns. This coincided with an improvement of the predominantly diurnal TACs, suggesting a PH-DBS-induced change in sleep patterns. Hypnograms after DBS demonstrated disrupted sleep and a prolonged period of wakefulness after midnight in both patients, which was reproduced the second night. Conclusions PH-DBS, a promising treatment for severe refractory TACs, affects sleep quality and pre-existing sleep disorders. This needs to be considered when treating patients with PH-DBS.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据