期刊
CEPHALALGIA
卷 31, 期 2, 页码 235-244出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/0333102410378051
关键词
Anxiety; chronic daily headache; depression; drug abuse; migraine; post-traumatic stress disorder; smoking
资金
- US National Institute of Mental Health (NIMH) [U01-MH60220]
- National Institute of Drug Abuse
- Substance Abuse and Mental Health Services Administration
- Robert Wood Johnson Foundation [044780]
- John W. Alden Trust
- GSK
- Pfizer
- NATIONAL INSTITUTE OF MENTAL HEALTH [U01MH060220] Funding Source: NIH RePORTER
Background: Post-traumatic stress disorder (PTSD) has been shown to be associated with migraine and drug abuse. Methods: This was an analysis of data from the National Comorbidity Survey Replication (NCS-R) to evaluate the association of PTSD in those with episodic migraine (EM) and chronic daily headache (CDH). Results: Our sample consisted of 5,692 participants. Lifetime and 12-month prevalence rates of PTSD were increased in those with EM and CDH. After adjustments, the lifetime odds ratio (OR) of PTSD was greater in those with EM (OR 3.07 confidence interval [CI]: 2.12, 4.46) compared to those without headache; was greater in men than women with EM (men: OR 6.86; CI: 3.11, 15.11; women: OR 2.77; CI: 1.83, 4.21); and was comparable or greater than the association between migraine with depression or anxiety. The lifetime OR of PTSD was also increased in CDH sufferers. The OR of illicit drug abuse was not increased in those with EM or CDH unless co-occurring with PTSD or depression. Conclusion: The lifetime and 12-month OR of PTSD is increased in those with migraine or CDH, and is greater in men than women with migraine. The lifetime and 12-month OR of illicit drug abuse is not increased in those with migraine or CDH unless co-occurring with PTSD or depression.
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