A simple, ring-closing metathesis reaction based approach to (+/-)-1,14-herbertenediol and (+/-)-11-epi-herbertenolide

A total synthesis of 1,14-herbertenediol via 11-epi-herbertenolide. and a formal total synthesis of tochuinyl acetate and dihydrotochuinyl acetate, employing a ring-closing metathesis reaction based methodology, are described. (C) 2001 Elsevier Science Ltd. All rights reserved.