The first synthesis of a calix[4](diseleno)crown ether as a sensor for ion-selective electrodes

Two calix[4](diseleno)crown ethers 3 and 4 were synthesized by reaction of the disodium salt of 1,3-propanediselanol with the preorganized 1,3-dibromoethoxylcalix[4]arenes 1 and 2. Compound 3 forms an interesting infinite sheet aggregate via self-inclusion and intermolecular Se . . . Se interactions in the solid state. Preliminary evaluation of 3 and 4 as ionophores for ion-selective electrodes (ISEs) is reported. (C) 2001 Elsevier Science Ltd. All rights reserved.