期刊
BONE MARROW TRANSPLANTATION
卷 29, 期 5, 页码 457-458出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/sj.bmt.1703379
关键词
hypereosinophilic syndrome; allogeneic stem cell transplantation; non-myeloablative conditioning
A male patient with hypereosinophilic syndrome (HES) underwent an allogeneic blood stem cell transplantation from a female donor following non-myeloablative conditioning consisting of a 2 Gy dose of TBI and fludarabine 30 mg/ml(2) intravenously on three days. Before transplantation 100% of the mitotic bone marrow cells of the patient showed a clonal karyotype abnormality. Three months after the transplantation eosinophilia had resolved and a chromosome analysis revealed normal female karyotype. The present study shows that stem cell transplantation after non-myeloablative conditioning may have curative potential for HES.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据