期刊
NEUROSCIENCE LETTERS
卷 320, 期 1-2, 页码 57-60出版社
ELSEVIER SCI IRELAND LTD
DOI: 10.1016/S0304-3940(02)00032-0
关键词
schizophrenia; interhemispheric transmission; lexical decision; hemispheric asymmetry; corpus callosum; interhemispheric transmission time
Interhemispheric transfer was investigated in 14 schizophrenia patients and 15 age- and sex-matched healthy controls in a lateralized lexical decision task. Words and pseudowords were tachistoscopically presented either to the left or to the right visual hemifield. Event-related potentials were determined from a 65-channel electroencephalogram. Information transfer between hemispheres was assessed by the interhemispheric transmission time (IHTT), the N1-latency difference between ipsilateral and contralateral hemisphere. Controls, but not schizophrenia patients showed significantly faster IHTT from the right to the left hemisphere for words, while IHTT from the left to the right hemisphere did not differ between groups and stimuli. These findings are interpreted in terms of a deficit in schizophrenia to transfer verbal information from the right to the left hemisphere via the corpus callosum. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.
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