期刊
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
卷 68, 期 1, 页码 440-443出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.68.1.440-443.2002
关键词
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Transfer of plasmid-borne antibiotic resistance genes in Escherichia coli wild-type strains is possible by transformation under naturally occurring conditions in oligotrophic, aquatic environments containing physiologic concentrations of calcium. In contrast, transformation is suppressed in nitrogen-rich body fluids like urine, a common habitat of uropathogenic strains. Current knowledge indicates that transformation of these E. coli wild-type strains is of no relevance for the acquisition of resistance in this clinically important environment.
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