期刊
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
卷 66, 期 3, 页码 679-681出版社
TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.66.679
关键词
1,4-dihydroxy-2-naphthoic acid; bifidogenic growth stimulator; Propionibacterium freudenreichii
We have found a new growth stimulator for bifidobacteria in the culture broth of Propionibacterium freudenrelchii ET-3. The bifidogenic growth stimulator (BGS) was purified by Diaion HP-20 column chromatography and preparative HPLC. Spectroscopic methods including H-1-NMR, UV, and LC-ESI-MS experiments indicated that the chemical structure of the bifidogenic growth stimulator was 1,4-dihydroxy-2-naphthoic acid (DHNA). Approximately 10 mg/L of DHNA was found to be produced in the culture broth of P. freudenreichii ET-3.
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