期刊
JOURNAL OF APPLIED PHYSIOLOGY
卷 92, 期 3, 页码 1125-1132出版社
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/japplphysiol.00296.2001
关键词
glucose metabolism; luteal phase
资金
- NATIONAL INSTITUTE ON AGING [R01AG014769] Funding Source: NIH RePORTER
- NIA NIH HHS [AG-14769] Funding Source: Medline
The purpose of this investigation was to determine plasma glucose kinetics and substrate oxidation in men and women during exercise relative to the lactate threshold (LT). Subjects cycled for 25 min at 70 and 90% of O-2 uptake ((V) over dot O-2) at LT (70 and 90% LT, respectively). Plasma glucose appearance (R.) and disappearance (R-d) were determined with a primed constant infusion of [6,6-H-2] glucose. There were no significant differences in glucose R-a between men [22.6 +/- 1.9 and 39.9 +/- 3.9 mumol.kg fat-free mass (FFM)(-1).min(-1) for 70 and 90% LT, respectively] and women (22.3 +/- 2.7 and 33.9 +/- 5.7 mumol.kg FFM-1.min(-1) for 70 and 90% LT, respectively). Similarly, there were no significant differences in glucose Rd between men(21.2 +/- 1.9 and 38.1 +/- 3.7 mumol.kgFFM(-1).min(-1) for 70 and 90% LT, respectively) and women (21.3 +/- 2.8 and 33.3 +/- 5.6 mumol . kg FFM-1 . min(-1) for 70 and 90% LT, respectively). Although there were no differences between genders in the relative contribution of carbohydrate (CHO) to total energy expenditure, the relative contribution of muscle glycogen to total CHO oxidation (75.8 +/- 3.2 and 64.2 +/- 8.0% for men and women, respectively, at 70% LT and 75.1 +/- 2.6 and 60.1 +/- 11.2% for men and women, respectively, at 90% LT) was lower in women. Consequently, the relative contribution of blood glucose to total CHO oxidation was significantly higher in women. These results indicate that although plasma glucose R. and Rd are similar in men and women, the relative contribution of muscle glycogen and blood glucose is significantly different in women during moderate-intensity exercise relative to LT.
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