期刊
CELLULAR SIGNALLING
卷 25, 期 10, 页码 1955-1961出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.cellsig.2013.04.009
关键词
Motility; Rho GTPases; Actin; Cancer; PI3K
类别
The last decades have witnessed an exponential increase in our knowledge of Rho GTPase signaling network which further highlighted the cross talk between these proteins and the complexity of their signaling pathways. In this review, we summarize the upstream and downstream players from Rho GTPases that are mainly involved in actin polymerization leading to cell motility and potentially playing a role in cancer cell metastasis. (C) 2013 The Authors. Published by Elsevier Inc. All rights reserved.
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