期刊
BIOINFORMATICS
卷 18, 期 3, 页码 500-501出版社
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/18.3.500
关键词
-
类别
资金
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM062118] Funding Source: NIH RePORTER
- NIGMS NIH HHS [R01 GM62118] Funding Source: Medline
Detecting Variability in Evolutionary Rates among GEnes (DIVERGE) is a software system to study functional divergence of a protein family by detecting site-specific change in evolutionary rate using a multiple alignment of amino acid sequences for a given phylogenetic tree. The program first conducts a statistical test for site-specific rate shifts along the tree, and predicting candidate amino acid residues responsible for functional divergence based on posterior analysis. These results can then be mapped on the 3D protein structure if available.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据