期刊
JOURNAL OF CELLULAR BIOCHEMISTRY
卷 -, 期 -, 页码 45-53出版社
WILEY-LISS
DOI: 10.1002/jcb.10404
关键词
magnetic resonance imaging; hexafluorobenzene; oxygen; tumor; tissue factor; antibody targeting
资金
- NCI NIH HHS [P20 CA86354, R01 CA079515, CA79515, R01 CA74951, CA54168, P20 CA086354] Funding Source: Medline
- NCRR NIH HHS [P41-RR02584, P41 RR002584] Funding Source: Medline
- NATIONAL CANCER INSTITUTE [R01CA074951, P20CA086354, R01CA079515, R01CA054168] Funding Source: NIH RePORTER
- NATIONAL CENTER FOR RESEARCH RESOURCES [P41RR002584] Funding Source: NIH RePORTER
One of the fundamental molecules governing the survival of mammalian cells is oxygen. Oxygen has gained particular significance in tumor developmental biology and oncology. An increasingly diverse array of methods is now available to characterize tumor oxygenation. This Prospect will consider a new method, Fluorocarbon Relaxometry using Echo planar imaging for Dynamic Oxygen Mapping (FREDOM), which we have recently developed for oximetry, examine application to a specific therapeutic example and place this technique in the context of other approaches.
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