期刊
JOURNAL OF CELLULAR BIOCHEMISTRY
卷 -, 期 -, 页码 88-95出版社
WILEY
DOI: 10.1002/jcb.10054
关键词
interleukin 17 (IL-17); gene therapy; hematopoiesis; T-cells; cytokines
Interleukin 17 (IL-17) is an essential proinflammatory T-cell derived cytokine with various biological actions. IL-17 was found to have a pivotal role in microbial host defense by interconnecting lymphoid and myeloid host defense. It also acts as a stimulatory hematopoietic cytokine by expanding myeloid progenitors and initiating proliferation of mature neutrophils. This article summarizes results to date on IL-17 research and discusses gene therapy based strategies that were employed to determine its biological functions and significance. A comprehensive working model for IL-17 is introduced.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据