期刊
CELLULAR AND MOLECULAR NEUROBIOLOGY
卷 31, 期 2, 页码 175-193出版社
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s10571-010-9605-x
关键词
Angiogenesis; Blood brain barrier; Mesenchymal stem cell; Microvasculature; Pericyte
资金
- The Japanese Ministry of Education, Culture, Sports, Science and Technology [C 19590992, C 22590937]
Brain pericytes are an important constituent of neurovascular unit. They encircle endothelial cells and contribute to the maturation and stabilization of the capillaries in the brain. Recent studies have revealed that brain pericytes play pivotal roles in a variety of brain functions, such as regulation of capillary flow, angiogenesis, blood brain barrier, immune responses, and hemostasis. In addition, brain pericytes are pluripotent and can differentiate into different lineages similar to mesenchymal stem cells. The brain pericytes are revisited as a key player to maintain brain function and repair brain damage.
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