相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Crystallographic Fragment Screening and Structure-Based Optimization Yields a New Class of Influenza Endonuclease Inhibitors
Joseph D. Bauman et al.
ACS CHEMICAL BIOLOGY (2013)
Structure-Based Discovery of the Novel Antiviral Properties of Naproxen against the Nucleoprotein of Influenza A Virus
Nathalie Lejal et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2013)
Inhibition of herpesvirus and influenza virus replication by blocking polymerase subunit interactions
Giorgio Palu et al.
ANTIVIRAL RESEARCH (2013)
A small molecule multi-kinase inhibitor reduces influenza A virus replication by restricting viral RNA synthesis
Luis Martinez-Gil et al.
ANTIVIRAL RESEARCH (2013)
The use of sialidase therapy for respiratory viral infections
John M. Nicholls et al.
ANTIVIRAL RESEARCH (2013)
Combination of MEK inhibitors and oseltamivir leads to synergistic antiviral effects after influenza A virus infection in vitro
Emanuel Haasbach et al.
ANTIVIRAL RESEARCH (2013)
Influenza virus resistance to neuraminidase inhibitors
Melanie Samson et al.
ANTIVIRAL RESEARCH (2013)
Favipiravir (T-705), a novel viral RNA polymerase inhibitor
Yousuke Furuta et al.
ANTIVIRAL RESEARCH (2013)
Identification of the first synthetic inhibitors of the type II transmembrane serine protease IMPRSS2 suitable for inhibition of influenza virus activation
Daniela Meyer et al.
BIOCHEMICAL JOURNAL (2013)
Discovery and synthesis of novel benzofurazan derivatives as inhibitors of influenza A virus
Ulrich Kessler et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
Lessons from Lipids in the Fight against Influenza
Adolfo Garcia-Sastre
CELL (2013)
The Lipid Mediator Protectin D1 Inhibits Influenza Virus Replication and Improves Severe Influenza
Masayuki Morita et al.
CELL (2013)
Lipidomic Profiling of Influenza Infection Identifies Mediators that Induce and Resolve Inflammation
Vincent C. Tam et al.
CELL (2013)
The NF-B inhibitor SC75741 efficiently blocks influenza virus propagation and confers a high barrier for development of viral resistance
Christina Ehrhardt et al.
CELLULAR MICROBIOLOGY (2013)
A peptide derived from the C-terminus of PB1 inhibits influenza virus replication by interfering with viral polymerase assembly
Chunfeng Li et al.
FEBS JOURNAL (2013)
Structure and assembly of the influenza A virus ribonucleoprotein complex
Wenjie Zheng et al.
FEBS LETTERS (2013)
Sialylneolacto-N-tetraose c (LSTc)-bearing Liposomal Decoys Capture Influenza A Virus
Gabriel L. Hendricks et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Discovery of Novel Dual Inhibitors of the Wild-Type and the Most Prevalent Drug-Resistant Mutant, S31N, of the M2 Proton Channel from Influenza A Virus
Jizhou Wang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Structural Investigation of Cycloheptathiophene-3-carboxamide Derivatives Targeting Influenza Virus Polymerase Assembly
Serena Massari et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Contribution of Double-Stranded RNA and CPSF30 Binding Domains of Influenza Virus NS1 to the Inhibition of Type I Interferon Production and Activation of Human Dendritic Cells
Irene Ramos et al.
JOURNAL OF VIROLOGY (2013)
Serum- and Glucocorticoid-Regulated Kinase 1 Is Required for Nuclear Export of the Ribonucleoprotein of Influenza A Virus
Judith G. Alamares-Sapuay et al.
JOURNAL OF VIROLOGY (2013)
SUMOylation Affects the Interferon Blocking Activity of the Influenza A Nonstructural Protein NS1 without Affecting Its Stability or Cellular Localization
Andres Santos et al.
JOURNAL OF VIROLOGY (2013)
Nucleozin Targets Cytoplasmic Trafficking of Viral Ribonucleoprotein-Rab11 Complexes in Influenza A Virus Infection
Maria Joao Amorim et al.
JOURNAL OF VIROLOGY (2013)
The RNA-binding domain of influenzavirus non-structural protein-1 cooperatively binds to virus-specific RNA sequences in a structure-dependent manner
Daniel Marc et al.
NUCLEIC ACIDS RESEARCH (2013)
Serum Amyloid P Is a Sialylated Glycoprotein Inhibitor of Influenza A Viruses
Emma R. Job et al.
PLOS ONE (2013)
Nonstructural Protein 1 of Influenza A Virus Interacts with Human Guanylate-Binding Protein 1 to Antagonize Antiviral Activity
Zixiang Zhu et al.
PLOS ONE (2013)
Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus
Jun Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
How academic labs can approach the drug discovery process as a way to synergize with big pharma
Arianna Loregian et al.
TRENDS IN MICROBIOLOGY (2013)
Systems Analysis of a RIG-I Agonist Inducing Broad Spectrum Inhibition of Virus Infectivity
Marie-Line Goulet et al.
PLOS PATHOGENS (2013)
Tmprss2 Is Essential for Influenza H1N1 Virus Pathogenesis in Mice
Bastian Hatesuer et al.
PLOS PATHOGENS (2013)
Monomeric Nucleoprotein of Influenza A Virus
Sylvie Chenavas et al.
PLOS PATHOGENS (2013)
The RNA polymerase of influenza A virus: mechanisms of viral transcription and replication
E. Fodor
ACTA VIROLOGICA (2013)
Development of an Anti-Influenza Drug Screening Assay Targeting Nucleoproteins with Tryptophan Fluorescence Quenching
Hui-Chen Hung et al.
ANALYTICAL CHEMISTRY (2012)
Human Cytomegalovirus Inhibitor AL18 Also Possesses Activity against Influenza A and B Viruses
Giulia Muratore et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2012)
Structure-based discovery of anti-influenza virus A compounds among medicines
Mayuko Fukuoka et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2012)
Effects of polyphenol compounds on influenza A virus replication and definition of their mechanism of action
Rossella Fioravanti et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2012)
Design, synthesis, and evaluation of novel small molecule inhibitors of the influenza virus protein NS1
Joseph J. Jablonski et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2012)
Influenza A virus-encoded NS1 virulence factor protein inhibits innate immune response by targeting IKK
Shijuan Gao et al.
CELLULAR MICROBIOLOGY (2012)
Recent Advances in Neuraminidase Inhibitor Development as Anti-influenza Drugs
Enguang Feng et al.
CHEMMEDCHEM (2012)
Highly Potent Inhibitors of Proprotein Convertase Furin as Potential Drugs for Treatment of Infectious Diseases
Gero L. Becker et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export
Liang Zhang et al.
JOURNAL OF CELL BIOLOGY (2012)
A novel family of peptides with potent activity against influenza A viruses
Marlynne Q. Nicol et al.
JOURNAL OF GENERAL VIROLOGY (2012)
A Phase II Study of DAS181, a Novel Host Directed Antiviral for the Treatment of Influenza Infection
Ronald B. Moss et al.
JOURNAL OF INFECTIOUS DISEASES (2012)
Design, Synthesis, and in Vitro Biological Evaluation of 1H-1,2,3-Triazole-4-carboxamide Derivatives as New Anti-influenza A Agents Targeting Virus Nucleoprotein
Huimin Cheng et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Strain-Specific Contribution of NS1-Activated Phosphoinositide 3-Kinase Signaling to Influenza A Virus Replication and Virulence
Juan Ayllon et al.
JOURNAL OF VIROLOGY (2012)
5′-Triphosphate-Short Interfering RNA: Potent Inhibition of Influenza A Virus Infection by Gene Silencing and RIG-I Activation
Li Lin et al.
JOURNAL OF VIROLOGY (2012)
Cross-neutralization of influenza A viruses mediated by a single antibody loop
Damian C. Ekiert et al.
NATURE (2012)
Identification of Small Molecules with Type I Interferon Inducing Properties by High-Throughput Screening
Luis Martinez-Gil et al.
PLOS ONE (2012)
Polymer-attached zanamivir inhibits synergistically both early and late stages of influenza virus infection
Chia Min Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Small molecule inhibitors of influenza A and B viruses that act by disrupting subunit interactions of the viral polymerase
Giulia Muratore et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Organization of the Influenza Virus Replication Machinery
Arne Moeller et al.
SCIENCE (2012)
An Overlapping Protein-Coding Region in Influenza A Virus Segment 3 Modulates the Host Response
B. W. Jagger et al.
SCIENCE (2012)
Highly Conserved Protective Epitopes on Influenza B Viruses
Cyrille Dreyfus et al.
SCIENCE (2012)
Emerging cellular targets for influenza antiviral agents
Konstantin H. Mueller et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2012)
A Novel Small Molecule Inhibitor of Influenza A Viruses that Targets Polymerase Function and Indirectly Induces Interferon
Mila Brum Ortigoza et al.
PLOS PATHOGENS (2012)
Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease
Rebecca M. DuBois et al.
PLOS PATHOGENS (2012)
Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza pH1N1 (2009) Polymerase
Eva Kowalinski et al.
PLOS PATHOGENS (2012)
Identification of Influenza Virus Inhibitors Targeting NS1A Utilizing Fluorescence Polarization-Based High-Throughput Assay
Eun Jeong Cho et al.
JOURNAL OF BIOMOLECULAR SCREENING (2012)
Intravenous Peramivir for Treatment of Influenza A and B Virus Infection in High-Risk Patients
Shigeru Kohno et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2011)
Redox Regulation of the Influenza Hemagglutinin Maturation Process: A New Cell-Mediated Strategy for Anti-Influenza Therapy
Rossella Sgarbanti et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
Antiviral activity of the MEK-inhibitor U0126 against pandemic H1N1v and highly pathogenic avian influenza virus in vitro and in vivo
Karoline Droebner et al.
ANTIVIRAL RESEARCH (2011)
Antiviral effect of a selective COX-2 inhibitor on H5N1 infection in vitro
Suki M. Y. Lee et al.
ANTIVIRAL RESEARCH (2011)
Synthesis and evaluation of quinoxaline derivatives as potential influenza NS1A protein inhibitors
Lei You et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)
Phenotypic and genotypic characterization of influenza virus mutants selected with the sialidase fusion protein DAS181
Gallen B. Triana-Baltzer et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2011)
High Mannose-binding Lectin with Preference for the Cluster of α1-2-Mannose from the Green Alga Boodlea coacta Is a Potent Entry Inhibitor of HIV-1 and Influenza Viruses
Yuichiro Sato et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Novel inhibitor of influenza non-structural protein 1 blocks multi-cycle replication in an RNase L-dependent manner
Marcin P. Walkiewicz et al.
JOURNAL OF GENERAL VIROLOGY (2011)
Generation and Characterization of Recombinant Pandemic Influenza A(H1N1) Viruses Resistant to Neuraminidase Inhibitors
Andres Pizzorno et al.
JOURNAL OF INFECTIOUS DISEASES (2011)
Attaching Zanamivir to a Polymer Markedly Enhances Its Activity Against Drug-resistant Strains of Influenza a Virus
Alisha K. Weight et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2011)
Exploring Organosilane Amines as Potent Inhibitors and Structural Probes of Influenza A Virus M2 Proton Channel
Jun Wang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Molecular Dynamics Simulation Directed Rational Design of Inhibitors Targeting Drug-Resistant Mutants of Influenza A Virus M2
Jun Wang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
How Do Aminoadamantanes Block the Influenza M2 Channel, and How Does Resistance Develop?
Hadas Leonov et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Generation and Comprehensive Analysis of an Influenza Virus Polymerase Cellular Interaction Network
Lionel Tafforeau et al.
JOURNAL OF VIROLOGY (2011)
Receptor Tyrosine Kinase Inhibitors Block Multiple Steps of Influenza A Virus Replication
Naveen Kumar et al.
JOURNAL OF VIROLOGY (2011)
Antioxidant Therapy as a Potential Approach to Severe Influenza-Associated Complications
Noboru Uchide et al.
MOLECULES (2011)
Identification of influenza virus inhibitors which disrupt of viral polymerase protein-protein interactions
Geoffrey Chase et al.
METHODS (2011)
Mechanism of Inhibition of Enveloped Virus Membrane Fusion by the Antiviral Drug Arbidol
Elodie Teissier et al.
PLOS ONE (2011)
Anti-Influenza Activity of Marchantins, Macrocyclic Bisbibenzyls Contained in Liverworts
Yuma Iwai et al.
PLOS ONE (2011)
Glycyrrhizin Exerts Antioxidative Effects in H5N1 Influenza A Virus-Infected Cells and Inhibits Virus Replication and Pro-Inflammatory Gene Expression
Martin Michaelis et al.
PLOS ONE (2011)
Increased Inflammatory Signaling and Lethality of Influenza H1N1 by Nuclear Thioredoxin-1
Young-Mi Go et al.
PLOS ONE (2011)
Inhibition of Influenza A Virus (H1N1) Fusion by Benzenesulfonamide Derivatives Targeting Viral Hemagglutinin
Lei Zhu et al.
PLOS ONE (2011)
Potent Neutralization of Influenza A Virus by a Single-Domain Antibody Blocking M2 Ion Channel Protein
Guowei Wei et al.
PLOS ONE (2011)
Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin
James R. R. Whittle et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis
Hans-Heinrich Hoffmann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
E339 ... R416 salt bridge of nucleoprotein as a feasible target for influenza virus inhibitors
Yu-Fang Shen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
The host interactome of influenza virus presents new potential targets for antiviral drugs
Megan L. Shaw
REVIEWS IN MEDICAL VIROLOGY (2011)
A Neutralizing Antibody Selected from Plasma Cells That Binds to Group 1 and Group 2 Influenza A Hemagglutinins
Davide Corti et al.
SCIENCE (2011)
A Highly Conserved Neutralizing Epitope on Group 2 Influenza A Viruses
Damian C. Ekiert et al.
SCIENCE (2011)
Induction and evasion of type I interferon responses by influenza viruses
Adolfo Garcia-Sastre
VIRUS RESEARCH (2011)
Effects of the Combination of Favipiravir (T-705) and Oseltamivir on Influenza A Virus Infections in Mice
Donald F. Smee et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
N-acetyl-L-cysteine (NAC) inhibits virus replication and expression of pro-inflammatory molecules in A549 cells infected with highly pathogenic H5N1 influenza A virus
Janina Geiler et al.
BIOCHEMICAL PHARMACOLOGY (2010)
Advances in the Structure-Based Design of the Influenza A Neuraminidase Inhibitors
Petar M. Mitrasinovic
CURRENT DRUG TARGETS (2010)
Targeting pandemic influenza: a primer on influenza antivirals and drug resistance
Ronald B. Moss et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2010)
Pharmacokinetics of oseltamivir: an oral antiviral for the treatment and prophylaxis of influenza in diverse populations
Brian E. Davies
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2010)
Influenza Hemagglutinin and Neuraminidase Membrane Glycoproteins
Steven J. Gamblin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Potent Inhibitors of Furin and Furin-like Proprotein Convertases Containing Decarboxylated P1 Arginine Mimetics
Gero L. Becker et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Novel Type II Transmembrane Serine Proteases, MSPL and TMPRSS13, Proteolytically Activate Membrane Fusion Activity of the Hemagglutinin of Highly Pathogenic Avian Influenza Viruses and Induce Their Multicycle Replication
Yuushi Okumura et al.
JOURNAL OF VIROLOGY (2010)
Human host factors required for influenza virus replication
Renate Koenig et al.
NATURE (2010)
Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication
Alexander Karlas et al.
NATURE (2010)
Identification of influenza A nucleoprotein as an antiviral target
Richard Y. Kao et al.
NATURE BIOTECHNOLOGY (2010)
Structures of influenza A proteins and insights into antiviral drug targets
Kalyan Das et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
High-throughput identification of compounds targeting influenza RNA-dependent RNA polymerase activity
Ching-Yao Su et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
5′PPP-RNA induced RIG-I activation inhibits drug-resistant avian H5N1 as well as 1918 and 2009 pandemic influenza virus replication
Priya Ranjan et al.
VIROLOGY JOURNAL (2010)
Treatment of respiratory syncytial virus with palivizumab: a systematic review
Jia Hu et al.
WORLD JOURNAL OF PEDIATRICS (2010)
Protection from the 2009 H1N1 Pandemic Influenza by an Antibody from Combinatorial Survivor-Based Libraries
Arun K. Kashyap et al.
PLOS PATHOGENS (2010)
CS-8958, a Prodrug of the Novel Neuraminidase Inhibitor R-125489, Demonstrates a Favorable Long-Retention Profile in the Mouse Respiratory Tract
Kumiko Koyama et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)
Large-Scale Sequence Analysis of M Gene of Influenza A Viruses from Different Species: Mechanisms for Emergence and Spread of Amantadine Resistance
Yuki Furuse et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)
Characteristics of arbidol-resistant mutants of influenza virus: Implications for the mechanism of anti-influenza action of arbidol
Irina A. Leneva et al.
ANTIVIRAL RESEARCH (2009)
T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections
Yousuke Furuta et al.
ANTIVIRAL RESEARCH (2009)
Autophagy is involved in influenza A virus replication
Zhi Zhou et al.
AUTOPHAGY (2009)
Design and Pharmacological Characterization of Inhibitors of Amantadine-Resistant Mutants of the M2 Ion Channel of Influenza A Virus
Victoria Balannik et al.
BIOCHEMISTRY (2009)
A Physical and Regulatory Map of Host-Influenza Interactions Reveals Pathways in H1N1 Infection
Sagi D. Shapira et al.
CELL (2009)
Influenza A Virus NS1 Targets the Ubiquitin Ligase TRIM25 to Evade Recognition by the Host Viral RNA Sensor RIG-I
Michaela Ulrike Gack et al.
CELL HOST & MICROBE (2009)
Structural insight into the essential PB1-PB2 subunit contact of the influenza virus RNA polymerase
Kanako Sugiyama et al.
EMBO JOURNAL (2009)
Thiazolides, a New Class of Anti-influenza Molecules Targeting Viral Hemagglutinin at the Post-translational Level
Jean Francois Rossignol et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Bcl-2 Expression and p38MAPK Activity in Cells Infected with Influenza A Virus IMPACT ON VIRALLY INDUCED APOPTOSIS AND VIRAL REPLICATION
Lucia Nencioni et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
High prevalence of amantadine resistance among circulating European porcine influenza A viruses
Andi Krumbholz et al.
JOURNAL OF GENERAL VIROLOGY (2009)
Novel Influenza Virus NS1 Antagonists Block Replication and Restore Innate Immune Function
Dipanwita Basu et al.
JOURNAL OF VIROLOGY (2009)
A Complicated Message: Identification of a Novel PB1-Related Protein Translated from Influenza A Virus Segment 2 mRNA
Helen M. Wise et al.
JOURNAL OF VIROLOGY (2009)
Detection and Characterization of Influenza A Virus PA-PB2 Interaction through a Bimolecular Fluorescence Complementation Assay
Joseph N. Hemerka et al.
JOURNAL OF VIROLOGY (2009)
Crystal structure of an avian influenza polymerase PAN reveals an endonuclease active site
Puwei Yuan et al.
NATURE (2009)
The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit
Alexandre Dias et al.
NATURE (2009)
Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses
Jianhua Sui et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Inhibition of Neuraminidase Inhibitor-Resistant Influenza Virus by DAS181, a Novel Sialidase Fusion Protein
Gallen B. Triana-Baltzer et al.
PLOS ONE (2009)
Identification of a PA-Binding Peptide with Inhibitory Activity against Influenza A and B Virus Replication
Kerstin Wunderlich et al.
PLOS ONE (2009)
Antibody Recognition of a Highly Conserved Influenza Virus Epitope
Damian C. Ekiert et al.
SCIENCE (2009)
MDCK cells that express proteases TMPRSS2 and HAT provide a cell system to propagate influenza viruses in the absence of trypsin and to study cleavage of HA and its inhibition
Eva Boettcher et al.
VACCINE (2009)
Cross-Protective Potential of a Novel Monoclonal Antibody Directed against Antigenic Site B of the Hemagglutinin of Influenza A Viruses
Reiko Yoshida et al.
PLOS PATHOGENS (2009)
Treatment of influenza A (H1N1) virus infections in mice and ferrets with cyanovirin-N
Donald F. Smee et al.
ANTIVIRAL RESEARCH (2008)
Arbidol: A broad-spectrum antiviral compound that blocks viral fusion
Y. S. Boriskin et al.
CURRENT MEDICINAL CHEMISTRY (2008)
Comment on: Concerns of using sialidase fusion protein as an experimental drug to combat seasonal and pandemic influenza
John M. Nicholls et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2008)
The multifunctional NS1 protein of influenza A viruses
Benjamin G. Hale et al.
JOURNAL OF GENERAL VIROLOGY (2008)
Hyperinduction of cyclooxygenase-2-mediated proinflammatory cascade: A mechanism for the pathogenesis of avian influenza H5N1 infection
Suki M. Y. Lee et al.
JOURNAL OF INFECTIOUS DISEASES (2008)
Crystal structure of the polymerase PAC-PB1N complex from an avian influenza H5N1 virus
Xiaojing He et al.
NATURE (2008)
The structural basis for an essential subunit interaction in influenza virus RNA polymerase
Eiji Obayashi et al.
NATURE (2008)
Drosophila RNAi screen identifies host genes important for influenza virus replication
Linhui Hao et al.
NATURE (2008)
Viral membrane fusion
Stephen C. Harrison
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)
Heterosubtypic Neutralizing Monoclonal Antibodies Cross-Protective against H5N1 and H1N1 Recovered from Human IgM+ Memory B Cells
Mark Throsby et al.
PLOS ONE (2008)
Analysis of the interaction of influenza virus polymerase complex with human cell factors
Nuria Jorba et al.
PROTEOMICS (2008)
Host factors for replication and transcription of the influenza virus genome
Kyosuke Nagata et al.
REVIEWS IN MEDICAL VIROLOGY (2008)
Hsp90 inhibitors reduce influenza virus replication in cell culture
Geoffrey Chase et al.
VIROLOGY (2008)
Development of an HTS assay for the search of anti-influenza agents targeting the interaction of viral RNA with the NS1 protein
Marta Maroto et al.
JOURNAL OF BIOMOLECULAR SCREENING (2008)
Evidence that the C-terminal PB2-binding region of the influenza A virus PB1 protein is a discrete α-helical domain
Emma L. Poole et al.
FEBS LETTERS (2007)
Lipid raft disruption by cholesterol depletion enhances influenza a virus budding from MDCK cells
Subrata Barman et al.
JOURNAL OF VIROLOGY (2007)
A novel class of potent NF-icB signaling inhibitors
Johann Leban et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
The interferon-inducible protein viperin inhibits influenza virus release by perturbing lipid rafts
Xiuyan Wang et al.
CELL HOST & MICROBE (2007)
Acetylsalicylic acid (ASA) blocks influenza virus propagation via its NF-κB-inhibiting activity
Igor Mazur et al.
CELLULAR MICROBIOLOGY (2007)
Peptide-mediated interference with influenza A virus polymerase
Alexander Ghanem et al.
JOURNAL OF VIROLOGY (2007)
Biochemical mechanism of hepatitis C virus inhibition by the broad-spectrum antiviral arbidol
Eve-Isabelle Pecheur et al.
BIOCHEMISTRY (2007)
Effect of the phosphatidylinositol 3-kinase/Akt pathway on influenza A virus propagation
Yeun-Kyung Shin et al.
JOURNAL OF GENERAL VIROLOGY (2007)
Involvement of Hsp90 in assembly and nuclear import of influenza virus RNA polymerase subunits
Tadasuke Naito et al.
JOURNAL OF VIROLOGY (2007)
Nuclear export of influenza A virus mRNAs requires ongoing RNA polymerase II activity
Maria-Joao Amorim et al.
TRAFFIC (2007)
Proteases essential for human influenza virus entry into cells and their inhibitors as potential therapeutic agents
Hiroshi Kido et al.
CURRENT PHARMACEUTICAL DESIGN (2007)
Influenza A virus NS1 protein activates the phosphatidylinositol 3-kinase (PI3K)/Akt pathway by direct interaction with the p85 subunit of PI3K
Yeun-Kyung Shin et al.
JOURNAL OF GENERAL VIROLOGY (2007)
Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness
Bruce D. Levy et al.
JOURNAL OF IMMUNOLOGY (2007)
Resolution phase of inflammation: Novel endogenous anti-inflammatory and proresolving lipid mediators and pathways
Charles N. Serhan
ANNUAL REVIEW OF IMMUNOLOGY (2007)
Recent anti-influenza strategies in multivalent sialyloligosaccharides and sialylmimetics approaches
Xue-Long Sun
CURRENT MEDICINAL CHEMISTRY (2007)
The mechanism by which influenza A virus nucleoprotein forms oligomers and binds RNA
Qiaozhen Ye et al.
NATURE (2006)
Inhibition of influenza virus infection by a novel antiviral peptide that targets viral attachment to cells
Jeremy C. Jones et al.
JOURNAL OF VIROLOGY (2006)
Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium
Eva Böttcher et al.
JOURNAL OF VIROLOGY (2006)
The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design
Rupert J. Russell et al.
NATURE (2006)
Cyanovirin-N inhibits hepatitis C virus entry by binding to envelope protein glycans
Francois Helle et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Combination chemotherapy, a potential strategy for reducing the emergence of drug-resistant influenza A variants
Natalia A. Ilyushina et al.
ANTIVIRAL RESEARCH (2006)
Membrane accumulation of influenza A virus hemagglutinin triggers nuclear export of the viral genome via protein kinase Cα-mediated activation of ERK signaling
Henju Marjuki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The primary function of RNA binding by the influenza A virus NS1 protein in infected cells:: Inhibiting the 2′-5′ oligo (A) synthetase/RNase L pathway
JY Min et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
The M2 proton channels of influenza A and B viruses
LH Pinto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Sialidase fusion protein as a novel broad-spectrum inhibitor of influenza virus infection
MP Malakhov et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2006)
Selective anti-cytomegalovirus compounds discovered by screening for inhibitors of subunit interactions of the viral polymerase
A Loregian et al.
CHEMISTRY & BIOLOGY (2006)
Polymer-bound 6′ sialyl-N-acetyllactosamine protects mice infected by influenza virus
AS Gambaryan et al.
ANTIVIRAL RESEARCH (2005)
Incidence of adamantane resistance among influenza A (H3N2) viruses isolated worldwide from 1994 to 2005: a cause for concern
RA Bright et al.
LANCET (2005)
Dimeric zanamivir conjugates with various linking groups are potent, long-lasting inhibitors of influenza neuraminidase including H5N1 avian influenza
SJF Macdonald et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Mechanism of action of T-705 against influenza virus
Y Furuta et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2005)
Disruption of protein-protein interactions: Towards new targets for chemotherapy
A Loregian et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2005)
Human and avian influenza viruses target different cell types in cultures of human airway epithelium
MN Matrosovich et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
MEK inhibition impairs influenza B virus propagation without emergence of resistant variants
S Ludwig et al.
FEBS LETTERS (2004)
Enfuvirtide: The first therapy to inhibit the entry of HIV-1 into host CD4 lymphocytes
T Matthews et al.
NATURE REVIEWS DRUG DISCOVERY (2004)
Active NF-κB signalling is a prerequisite for influenza virus infection
F Nimmerjahn et al.
JOURNAL OF GENERAL VIROLOGY (2004)
Endocytosis of influenza viruses
M Lakadamyali et al.
MICROBES AND INFECTION (2004)
NF-κB-dependent induction of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas/FasL is crucial for efficient influenza virus propagation
WJ Wurzer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Protection against lethal influenza virus challenge by RNA interference in vivo
SM Tompkins et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
The two NF-κB activation pathways and their role in innate and adaptive immunity
G Bonizzi et al.
TRENDS IN IMMUNOLOGY (2004)
Influenza virus hemagglutinin concentrates in lipid raft microdomains for efficient viral fusion
M Takeda et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Inhibition of influenza infection by glutathione
JY Cai et al.
FREE RADICAL BIOLOGY AND MEDICINE (2003)
Use of a pharmacophore model to discover a new class of influenza endonuclease inhibitors
KEB Parkes et al.
JOURNAL OF MEDICINAL CHEMISTRY (2003)
Cyanovirin-N binds to the viral surface glycoprotein, GP1,2 and inhibits infectivity of Ebola virus
LG Barrientos et al.
ANTIVIRAL RESEARCH (2003)
Structure-activity relationships for a series of thiobenzamide influenza fusion inhibitors derived from 1,3,3-trimethyl-5-hydroxy-cyclohexylmethylamine
KL Yu et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2002)
Effect of antioxidants on apoptosis induced by influenza virus infection: inhibition of viral gene replication and transcription with pyrrolidine dithiocarbarnate
N Uchide et al.
ANTIVIRAL RESEARCH (2002)
Cleavage of influenza A virus hemagglutinin in human respiratory epithelium is cell associated and sensitive to exogenous antiproteases
OP Zhirnov et al.
JOURNAL OF VIROLOGY (2002)
Synthesis and anti-influenza evaluation of polyvalent sialidase inhibitors bearing 4-guanidino-Neu5Ac2en derivatives
T Honda et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2002)
Polymeric inhibitor of influenza virus attachment protects mice from experimental influenza infection
AS Gambaryan et al.
ANTIVIRAL RESEARCH (2002)
The influenza virus nucleoprotein: a multifunctional RNA-binding protein pivotal to virus replication
A Portela et al.
JOURNAL OF GENERAL VIROLOGY (2002)
In vitro and in vivo activities of anti-influenza virus compound T-705
Y Furuta et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2002)
Fine mapping of the subunit binding sites of influenza virus RNA polymerase
Y Ohtsu et al.
MICROBIOLOGY AND IMMUNOLOGY (2002)
A novel influenza A virus mitochondrial protein that induces cell death
WS Chen et al.
NATURE MEDICINE (2001)
Inhibition of nuclear export of ribonucleoprotein complexes of influenza virus by leptomycin B
K Watanabe et al.
VIRUS RESEARCH (2001)
Functional analysis of PA binding by influenza a virus PB1: Effects on polymerase activity and viral infectivity
DR Perez et al.
JOURNAL OF VIROLOGY (2001)
Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade
S Pleschka et al.
NATURE CELL BIOLOGY (2001)
Influenza virus NS1 protein counteracts PKR-mediated inhibition of replication
M Bergmann et al.
JOURNAL OF VIROLOGY (2000)
Influenza virus-induced NF-κB-dependent gene expression is mediated by overexpression of viral proteins and involves oxidative radicals and activation of IκB kinase
E Flory et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
p38 mitogen-activated protein kinase and c-Jun-NH2-terminal kinase regulate RANTES production by influenza virus-infected human bronchial epithelial cells
K Kujime et al.
JOURNAL OF IMMUNOLOGY (2000)
Influenza virus neuraminidase inhibitors
LV Gubareva et al.
LANCET (2000)
Multiple antiviral activities of cyanovirin-N: Blocking of human immunodeficiency virus type 1 gp120 interaction with CD4 and coreceptor and inhibition of diverse enveloped viruses
B Dey et al.
JOURNAL OF VIROLOGY (2000)