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SOCS1 cooperates with FLT3-ITD in the development of myeloproliferative disease by promoting the escape from external cytokine control
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BLOOD (2012)
Adaptor protein Lnk binds to and inhibits normal and leukemic FLT3
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BLOOD (2012)
Ectopic expression of Flt3 kinase inhibits proliferation and promotes cell death in different human cancer cell lines
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Role of SOCS1 in tumor progression and therapeutic application
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Suppressor of Cytokine Signaling 6 (SOCS6) Negatively Regulates Flt3 Signal Transduction through Direct Binding to Phosphorylated Tyrosines 591 and 919 of Flt3
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Suppression of SOCS3 in macrophages prevents cancer metastasis by modifying macrophage phase and MCP2/CCL8 induction
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SOCS1 controls liver regeneration by regulating HGF signaling in hepatocytes
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The SOCS2 Ubiquitin Ligase Complex Regulates Growth Hormone Receptor Levels
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Higher expression levels of SOCS 1,3,4,7 are associated with earlier tumour stage and better clinical outcome in human breast cancer
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A new polycythaemia vera-associated SOCS3 SH2 mutant (SOCS3F136L) cannot regulate erythropoietin responses
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