相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
Hiroshi Nishimasu et al.
CELL (2014)
Improving CRISPR-Cas nuclease specificity using truncated guide RNAs
Yanfang Fu et al.
NATURE BIOTECHNOLOGY (2014)
Dimeric CRISPR RNA-guided Fokl nucleases for highly specific genome editing
Shengdar Q. Tsai et al.
NATURE BIOTECHNOLOGY (2014)
Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems
Ines Fonfara et al.
NUCLEIC ACIDS RESEARCH (2014)
Efficient engineering of a bacteriophage genome using the type I-E CRISPR-Cas system
Ruth Kiro et al.
RNA BIOLOGY (2014)
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
Martin Jinek et al.
SCIENCE (2014)
Surrogate reporter-based enrichment of cells containing RNA-guided Cas9 nuclease-induced mutations
Suresh Ramakrishna et al.
NATURE COMMUNICATIONS (2014)
Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
Lei S. Qi et al.
CELL (2013)
One-Step Generation of Mice Carrying Reporter and Conditional Alleles by CRISPR/Cas-Mediated Genome Engineering
Hui Yang et al.
CELL (2013)
Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
F. Ann Ran et al.
CELL (2013)
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
Luke A. Gilbert et al.
CELL (2013)
Processing-Independent CRISPR RNAs Limit Natural Transformation in Neisseria meningitidis
Yan Zhang et al.
MOLECULAR CELL (2013)
CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
Prashant Mali et al.
NATURE BIOTECHNOLOGY (2013)
DNA targeting specificity of RNA-guided Cas9 nucleases
Patrick D. Hsu et al.
NATURE BIOTECHNOLOGY (2013)
Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease
Seung Woo Cho et al.
NATURE BIOTECHNOLOGY (2013)
High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity
Vikram Pattanayak et al.
NATURE BIOTECHNOLOGY (2013)
High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
Yanfang Fu et al.
NATURE BIOTECHNOLOGY (2013)
RNA-guided editing of bacterial genomes using CRISPR-Cas systems
Wenyan Jiang et al.
NATURE BIOTECHNOLOGY (2013)
RNA-guided gene activation by CRISPR-Cas9-based transcription factors
Pablo Perez-Pinera et al.
NATURE METHODS (2013)
CRISPR RNA-guided activation of endogenous human genes
Morgan L. Maeder et al.
NATURE METHODS (2013)
Orthogonal Cas9 proteins for RNA-guided gene regulation and editing
Kevin M. Esvelt et al.
NATURE METHODS (2013)
Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system
David Bikard et al.
NUCLEIC ACIDS RESEARCH (2013)
Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems
James E. DiCarlo et al.
NUCLEIC ACIDS RESEARCH (2013)
Simultaneous Screening and Validation of Effective Zinc Finger Nucleases in Yeast
Ling Wang et al.
PLOS ONE (2013)
Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis
Zhonggang Hou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
The tracrRNA and Cas9 families of type II CRISPR-Cas immunity systems
Krzysztof Chylinski et al.
RNA BIOLOGY (2013)
crRNA and tracrRNA guide Cas9-mediated DNA interference in Streptococcus thermophilus
Tautvydas Karvelis et al.
RNA BIOLOGY (2013)
RNA-Guided Human Genome Engineering via Cas9
Prashant Mali et al.
SCIENCE (2013)
Multiplex Genome Engineering Using CRISPR/Cas Systems
Le Cong et al.
SCIENCE (2013)
RNA-guided genetic silencing systems in bacteria and archaea
Blake Wiedenheft et al.
NATURE (2012)
Cleavage of Phage DNA by the Streptococcus thermophilus CRISPR3-Cas System
Alfonso H. Magadan et al.
PLOS ONE (2012)
Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
Giedrius Gasiunas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jinek et al.
SCIENCE (2012)
CRISPR-Cas Systems in Bacteria and Archaea: Versatile Small RNAs for Adaptive Defense and Regulation
Devaki Bhaya et al.
ANNUAL REVIEW OF GENETICS, VOL 45 (2011)
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
Elitza Deltcheva et al.
NATURE (2011)
Evolution and classification of the CRISPR-Cas systems
Kira S. Makarova et al.
NATURE REVIEWS MICROBIOLOGY (2011)
The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli
Rimantas Sapranauskas et al.
NUCLEIC ACIDS RESEARCH (2011)
CRISPR/Cas, the Immune System of Bacteria and Archaea
Philippe Horvath et al.
SCIENCE (2010)
Hierarchy of nonhomologous end-joining, single-strand annealing and gene conversion at site-directed DNA double-strand breaks
Wael Y. Mansour et al.
NUCLEIC ACIDS RESEARCH (2008)
Diversity, activity, and evolution of CRISPR loci in Streptococcus thermophilus
Philippe Horvath et al.
JOURNAL OF BACTERIOLOGY (2008)
High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method
R. Daniel Gietz et al.
NATURE PROTOCOLS (2007)
Large-scale high-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method
R. Daniel Gietz et al.
NATURE PROTOCOLS (2007)
A novel yeast-based reporter assay system for the sensitive detection of genotoxic agents mediated by a DNA damage-inducible LexA-GAL4 protein
K Ichikawa et al.
JOURNAL OF BIOCHEMISTRY (2006)
Yeast vectors for integration at the HO locus
Warren P. Voth et al.
NUCLEIC ACIDS RESEARCH (2001)