期刊
CELLULAR AND MOLECULAR LIFE SCIENCES
卷 71, 期 21, 页码 4081-4087出版社
SPRINGER BASEL AG
DOI: 10.1007/s00018-014-1682-4
关键词
Nascent tumor; Elimination; Reprogramming; Microvesicle
资金
- Hungarian Scientific Research Fund (OTKA) [K100295]
A growing body of experimental evidence supports the diagnostic relevance of circulating microRNAs in various diseases including cancer. The biological relevance of circulating microRNAs is, however, largely unknown, particularly in healthy individuals. Here, we propose a hypothesis based on the relative abundance of microRNAs with predominant tumor suppressor activity in the blood of healthy individuals. According to our hypothesis, certain sets of circulating microRNAs might function as a tumor surveillance mechanism exerting continuous inhibition on tumor formation. The microRNA-mediated tumor surveillance might complement cancer immune surveillance.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据