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Posttranslational regulation of the NKG2D ligand Mult1 in response to cell stress
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JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Normally occurring NKG2D+CD4+ T cells are immunosuppressive and inversely correlated with disease activity in juvenile-onset lupus
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Cancer-Expanded Myeloid-Derived Suppressor Cells Induce Anergy of NK Cells through Membrane-Bound TGF-beta 1
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Selective induction of expression of a ligand for the NKG2D receptor by proteasome inhibitors
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Estradiol regulates MICA expression in human endometrial cells
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NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy
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Small intestinal CD8(+)TCR gamma delta(+)NKG2A(+) intraepithelial lymphocytes have attributes of regulatory cells in patients with celiac disease
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Human tumor-derived exosomes down-modulate NKG2D expression
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Two novel NKG2D ligands of the mouse H60 family with differential expression patterns and binding affinities to NKG2D
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Human microRNAs regulate stress-induced immune responses mediated by the receptor NKG2D
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NATURE IMMUNOLOGY (2008)
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ONCOGENE (2008)
A role for NKG2D in NK cell-mediated resistance to poxvirus disease
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PLOS PATHOGENS (2008)
Down-regulation of NKG2D and NKp80 ligands by Kaposi's sarcoma-associated herpesvirus K5 protects against NK cell cytotoxicity
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
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PROTEIN ENGINEERING DESIGN & SELECTION (2008)
NKG2D receptor signaling enhances cytolytic activity by virus-specific CD8+ T cells:: Evidence for a protective role in virus-induced encephalitis
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JOURNAL OF VIROLOGY (2008)
NKG2D ligand expression in AML increases in response to HDAC inhibitor valproic acid and contributes to allorecognition by NK-cell lines with single KIR-HLA class I specificities
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NKG2D signaling is coupled to the interleukin 15 receptor signaling pathway
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SCIENCE (2007)
An association between the MICA-A5.1 allele and an increased susceptibility to oral squamous cell carcinoma in Japanese patients
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JOURNAL OF ORAL PATHOLOGY & MEDICINE (2007)
RAET1E2, a soluble isoform of the UL16-binding protein RAET1E produced by tumor cells, inhibits NKG2D-mediated NK cytotoxicity
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JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Zoonotic orthopoxviruses encode a high-affinity antagonist of NKG2D
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JOURNAL OF EXPERIMENTAL MEDICINE (2007)
CD4+NKG2D+ T cells in Crohn's disease mediate inflammatory and cytotoxic responses through MICA interactions
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Disulphide-isomerase-enabled shedding of tumour-associated NKG2D ligands
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Association of polymorphic extracellular domains of MICA with cervical cancer in northeastern Thai population
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NKp46 and NKG2D recognition of infected dendritic cells is necessary for NK cell activation in the human response to influenza infection
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JOURNAL OF IMMUNOLOGY (2007)
HLA and MICA associations with head and neck squamous cell carcinoma
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Promoter region architecture and transcriptional regulation of the genes for the MHC class I-related chain A and B Ligands of NKG2D
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JOURNAL OF IMMUNOLOGY (2007)
Human immunodeficiency virus 1 Nef protein downmodulates the ligands of the activating receptor NKG2D and inhibits natural killer cell-mediated cytotoxicity
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JOURNAL OF GENERAL VIROLOGY (2007)
The switch from latent to productive infection in Epstein-Barr virus-infected B cells is associated with sensitization to NK cell killing
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JOURNAL OF VIROLOGY (2007)
Increased susceptibility to liver injury in hepatitis B virus transgenic mice involves NKG2D-ligand interaction and natural killer cells
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Expression and function of NKG2D in CD4+ T cells specific for human cytomegalovirus
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EUROPEAN JOURNAL OF IMMUNOLOGY (2006)
TGF-β and metalloproteinases differentially suppress NKG2D ligand surface expression on malignant glioma cells
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BRAIN (2006)
The herpesviral Fc receptor fcr-1 down-regulates the NKG2D ligands MULT-1 and H60
Tihana Lenac et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Down-regulation of the NKG2D ligand MICA by the human cytomegalovirus glycoprotein UL142
NJ Chalupny et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Fas ligand-mediated paracrine T cell regulation by the receptor NKG2D in tumor immunity
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NATURE IMMUNOLOGY (2006)
Therapy-induced antibodies to MHC class I chain-related protein A antagonize immune suppression and stimulate antitumor cytotoxicity
Masahisa Jinushi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Celiac disease- Sandwiched between innate and adaptive immunity
Dariusz Stepniak et al.
HUMAN IMMUNOLOGY (2006)
A novel bispecific protein (ULBP2-BB4) targeting the NKG2D receptor on natural killer (NK) cells and CD138 activates NK cells and has potent antitumor activity against human multiple myeloma in vitro and in vivo
EP von Strandmann et al.
BLOOD (2006)
Proteolytic release of soluble UL16-binding protein 2 from tumor cells
I Waldhauer et al.
CANCER RESEARCH (2006)
How NKG2D ligands trigger autoimmunity?
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HUMAN IMMUNOLOGY (2006)
A role for activation-induced cytidine deaminase in the host response against a transforming retrovirus
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IMMUNITY (2006)
Silencing human NKG2D, DAP10, and DAP12 reduces cytotoxicity of activated CD8+ T cells and NK cells
M Karimi et al.
JOURNAL OF IMMUNOLOGY (2005)
CD4+ CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-β-dependent manner
F Ghiringhelli et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
NKG2D function protects the host from tumor initiation
MJ Smyth et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillance
DE Oppenheim et al.
NATURE IMMUNOLOGY (2005)
Function of NKG2D in natural killer cell-mediated rejection of mouse bone marrow grafts
K Ogasawara et al.
NATURE IMMUNOLOGY (2005)
The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor
S Gasser et al.
NATURE (2005)
Systemic NKG2D down-regulation impairs NK and CD8 T cell responses in vivo
K Wiemann et al.
JOURNAL OF IMMUNOLOGY (2005)
The activating NKG2D receptor assembles in the membrane with two signaling dimers into a hexameric structure
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DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
J Bartkova et al.
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Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
VG Gorgoulis et al.
NATURE (2005)
Selective down-regulation of the NKG2D ligand H60 by mouse cytomegalovirus m155 glycoprotein
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JOURNAL OF VIROLOGY (2005)
NK cell activation through the NKG2D ligand MULT-1 is selectively prevented by the glycoprotein encoded by mouse cytomegalovirus gene m145
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JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Downregulation and/or release of NKG2D ligands as immune evasion strategy of human neuroblastoma
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NEOPLASIA (2004)
Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease
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IMMUNITY (2004)
A structural basis for the association of DAP12 with mouse, but not human, NKG2D
DB Rosen et al.
JOURNAL OF IMMUNOLOGY (2004)
Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D
L Bacon et al.
JOURNAL OF IMMUNOLOGY (2004)
Elevated TGF-β1 secretion and down-modulation of NKG2D underlies impaired NK cytotoxicity in cancer patients
JC Lee et al.
JOURNAL OF IMMUNOLOGY (2004)
NKG2D blockade prevents autoimmune diabetes in NOD mice
K Ogasawara et al.
IMMUNITY (2004)
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ANNUAL REVIEW OF IMMUNOLOGY (2004)
Roles of the NKG2D immunoreceptor and its ligands
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GASTROENTEROLOGY (2003)
Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rhe'umatoid arthritis
V Groh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Human cytomegalovirus glycoprotein UL16 causes intracellular sequestration of NKG2D ligands, protecting against natural killer cell cytotoxicity
C Dunn et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
NKG2D-mediated natural killer cell protection against cytomegalovirus is impaired by viral gp40 modulation of retinoic acid early inducible 1 gene molecules
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JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Symmetry recognizing asymmetry: Analysis of the interactions between the C-type lectin-like immunoreceptor NKG2D and MHC class I-like ligands
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A novel ligand for the NKG2D receptor activates NK cells and macrophages and induces tumor immunity
A Diefenbach et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2003)
Selective intracellular retention of virally induced NKG2D ligands by the human cytomegalovirus UL16 glycoprotein
SA Welte et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2003)
Regulation of Akt-dependent cell survival by Syk and Rac
K Jiang et al.
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Impairment of NK cell function by NKG2D modulation in NOD mice
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IMMUNITY (2003)
Thermodynamic analysis of degenerate recognition by the NKG2D immunoreceptor: Not induced fit but rigid adaptation
BJ McFarland et al.
IMMUNITY (2003)
NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation
S Gilfillan et al.
NATURE IMMUNOLOGY (2002)
Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D
A Diefenbach et al.
NATURE IMMUNOLOGY (2002)
Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation
V Groh et al.
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Cutting edge: Down-regulation of MICA on human tumors by proteolytic shedding
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JOURNAL OF IMMUNOLOGY (2002)
Cutting edge: Murine UL16-binding protein-like transcript 1: A newly described transcript encoding a high-affinity ligand for marine NKG2D
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JOURNAL OF IMMUNOLOGY (2002)
HLA-DRB1 and MHC class 1 chain-related A haplotypes in Basque families with celiac disease
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MCMV glycoprotein gp40 confers virus resistance to CD8+ T cells and NK cells in vivo
A Krmpotic et al.
NATURE IMMUNOLOGY (2002)
Syk regulation of phosphoinositide 3-kinase-dependent NK cell function
K Jiang et al.
JOURNAL OF IMMUNOLOGY (2002)
A cluster of ten novel MHC class I related genes on human chromosome 6q24.2-q25.3
M Radosavljevic et al.
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Ectopic expression of retinoic acid early inducible-1 gene (RAE-1) permits natural killer cell-mediated rejection of a MHC class I-bearing tumor in vivo
A Cerwenka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity
A Diefenbach et al.
NATURE (2001)
Typing for all known MICA alleles by group-specific PCR and SSOP
YZ Zhang et al.
HUMAN IMMUNOLOGY (2001)
Interactions of human NKG2D with its ligands MICA, MICB, and homologs of the mouse RAE-1 protein family
A Steinle et al.
IMMUNOGENETICS (2001)
Crystal structure of the murine NK cell-activating receptor NKG2D at 1.95 Å
DW Wolan et al.
NATURE IMMUNOLOGY (2001)
Costimulation of CD8αβ T cells by NKG2D via engagement by MIC induced on virus-infected cells
V Groh et al.
NATURE IMMUNOLOGY (2001)
ULBPs, novel MHC class I-related molecules bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor
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Estrogens in the causation of breast, endometrial and ovarian cancers - evidence and hypotheses from epidemiological findings
I Persson
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2000)
DAP10 and DAP12 form distinct, but functionally cooperative, receptor complexes in natural killer cells
J Wu et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages
A Diefenbach et al.
NATURE IMMUNOLOGY (2000)
Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice
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IMMUNITY (2000)
Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice
MK Kennedy et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
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