期刊
CELLULAR AND MOLECULAR LIFE SCIENCES
卷 67, 期 22, 页码 3785-3795出版社
SPRINGER BASEL AG
DOI: 10.1007/s00018-010-0447-y
关键词
Caveolin; Caveolae; Intracellular signaling; Neuron; Membrane receptor; G-protein
资金
- NIGMS NIH HHS [T32 GM008471] Funding Source: Medline
Caveolin proteins physically interact with and compartmentalize membrane-localized signaling proteins to facilitate high-fidelity intracellular signaling. Though primarily studied outside the nervous system, recent investigations have revealed that caveolin proteins are key modulators of a variety of neuronal intracellular signaling pathways. Through both protein aggregation and segregation, caveolin proteins can exert positive and negative influences on intracellular signaling. This review will detail recent findings regarding caveolin function in the brain.
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