期刊
BIOELECTROCHEMISTRY
卷 55, 期 1-2, 页码 89-92出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/S1567-5394(01)00162-1
关键词
torque generation; proton turbine; Brownian ratchet
Both the bacterial flagellar motor and the H+/ATP synthase are membrane-bound macromolecular complexes in which the movement of protons through channels across the membrane is coupled to the rotation of a part of the complex around an axis perpendicular to the membrane. Despite this similarity, the two devices are designed for quite different functions. The flagellar motor is responsible for a practically smooth rotation of the flagellar filament in order to propel the cell. Smooth rotation is not essential for the H+/ATP synthase, which accumulates torque by twisting a rod-shaped structure. Possible mechanisms for generating torque in the two devices are presented, based on the models which have been proposed. The performances of the various mechanisms are discussed. (C) 2002 Elsevier Science B.V. All rights reserved.
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