期刊
JOURNAL OF FLUID MECHANICS
卷 767, 期 -, 页码 -出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/jfm.2015.69
关键词
biological fluid dynamics; capsule/cell dynamics; low-Reynolds-number flows
资金
- ANR CAPSHYDR [11-BS09-013-02]
- Labex MEC [ANR-11-LABX-0092]
- A*MIDEX [ANR-11-IDEX-0001-02]
- CNES
- project Equip@Meso [ANR-10-EQPX-29-01]
Soft bio-microcapsules are drops bounded by a thin elastic shell made of cross-linked proteins. Their shapes and their dynamics in flow depend on their membrane constitutive law characterized by shearing and area-dilatation resistance. The deformations of such capsules are investigated experimentally in planar elongation flows and compared with numerical simulations for three bidimensional models: Skalak, neo-Hookean and generalized Hooke. An original cross-flow microfluidic set-up allows the visualization of the deformed shape in the two perpendicular main fields of view. Whatever the elongation rate, the three semi-axis lengths of the ellipsoid fitting the experimental shape are measured up to 180% of stretching of the largest axis. The geometrical analysis in the two views is sufficient to determine the constitutive law and the Poisson ratio of the membrane Without a preliminary knowledge of the shear elastic modulus G. We conclude that the membrane of human serum albumin capsules obeys the generalized Hooke law with a Poisson ratio of 0.4. The shear elastic modulus is then determined by the combination of numerical and experimental variations of the Taylor parameter with the capillary number.
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