期刊
CELLULAR & MOLECULAR IMMUNOLOGY
卷 7, 期 3, 页码 204-210出版社
CHIN SOCIETY IMMUNOLOGY
DOI: 10.1038/cmi.2010.20
关键词
Foxp3; Treg; immunosuppression and plasticity
类别
资金
- NIH/NIAID [K99/R00]
- NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [R00AI072956, K99AI072956] Funding Source: NIH RePORTER
Foxp3-expressing regulatory T cells (Tregs) were originally identified as critical in maintaining self-tolerance and immune homeostasis. The immunosuppressive functions of Tregs are widely acknowledged and have been extensively studied. Recent studies have revealed many diverse roles of Tregs in shaping the immune system and the inflammatory response. This review will discuss our efforts as well as the efforts of others towards understanding the multifaceted function of Tregs in immune regulation. Cellular & Molecular Immunology (2010) 7, 204-210; doi:10.1038/cmi.2010.20; published online 12 April 2010
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