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Recent advances in the synthesis of 1,3-diketones

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CURRENT ORGANIC CHEMISTRY
卷 7, 期 16, 页码 1691-1711

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BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1385272033486233

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The most recent achievements in the construction of the 1,3-diketone moiety are reviewed. Though both classical and modern approaches to the synthesis of 1,3-diketones are compared and analyzed in terms of efficiency, functional group compatibility, regio-, and stereoselectivity, main attention is paid to recently discovered methods based on rearrangements and concerted mechanisms. Molecular structure investigations, appearance in nature, and biological activity of 1,3-diketones are also briefly reviewed.

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