期刊
CELL STEM CELL
卷 14, 期 3, 页码 267-269出版社
CELL PRESS
DOI: 10.1016/j.stem.2014.02.010
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资金
- MRC [G0701448] Funding Source: UKRI
- Medical Research Council [G0701448] Funding Source: researchfish
- Medical Research Council [G0701448] Funding Source: Medline
The limited supply and expansion capacity of primary human hepatocytes presents major challenges for pharmaceutical applications and development of cell-based therapies for liver diseases. Now in Cell Stem Cell, two papers demonstrate efficient direct reprogramming of human fibroblasts into induced hepatocytes, which exhibit metabolic properties similar to primary hepatocytes.
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