期刊
CELL STEM CELL
卷 15, 期 4, 页码 406-409出版社
CELL PRESS
DOI: 10.1016/j.stem.2014.09.013
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资金
- Academy of Medical Sciences (AMS) [AMS-SGCL7-Rashid] Funding Source: researchfish
- Medical Research Council [MR/L006537/1] Funding Source: researchfish
- MRC [MR/L006537/1] Funding Source: UKRI
- Medical Research Council [MR/L006537/1] Funding Source: Medline
While cell therapies hold great potential for treating many conditions, their utility for treating patients that require whole organ replacement is unclear. To address this challenge, we propose using genetically engineered organ niches in large animals to generate human organs from pluripotent stem cells and discuss the hurdles facing such strategies.
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