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When Fibroblasts MET iPSCs

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CELL STEM CELL
卷 7, 期 1, 页码 5-6

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CELL PRESS
DOI: 10.1016/j.stem.2010.05.018

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Two independent studies by Li et al. (2010) and Samavarchi-Tehrani et al. (2010) in this issue of Cell Stem Cell suggest that a mesenchymal-to-epithelial transition is a critical initiating event during the derivation of induced pluripotent stem cells (iPSCs) from fibroblasts, indicating remarkable similarities between cellular reprogramming, development, and cancer.

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