相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Induction of autophagy and senescence by knockdown of ROC1 E3 ubiquitin ligase to suppress the growth of liver cancer cells
D. Yang et al.
CELL DEATH AND DIFFERENTIATION (2013)
Functional characterization of SAG/RBX2/ROC2/RNF7, an antioxidant protein and an E3 ubiquitin ligase
Yi Sun et al.
PROTEIN & CELL (2013)
Cullin-3 protein expression levels correlate with breast cancer progression
Kelly K. Haagenson et al.
CANCER BIOLOGY & THERAPY (2012)
The Nedd8-Activating Enzyme Inhibitor MLN4924 Induces Autophagy and Apoptosis to Suppress Liver Cancer Cell Growth
Zhongguang Luo et al.
CANCER RESEARCH (2012)
An integrated view of cyclin E function and regulation
Ka Tat Siu et al.
CELL CYCLE (2012)
CUL4B ubiquitin ligase in mouse development: A model for human X-linked mental retardation syndrome?
Yongchao Zhao et al.
CELL RESEARCH (2012)
Essential role of the CUL4B ubiquitin ligase in extra-embryonic tissue development during mouse embryogenesis
Liren Liu et al.
CELL RESEARCH (2012)
MLN4924: a novel first-in-class inhibitor of NEDD8-activating enzyme for cancer therapy
Steffan T. Nawrocki et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2012)
Tumor suppressor functions of FBW7 in cancer development and progression
Zhiwei Wang et al.
FEBS LETTERS (2012)
Understanding Cullin-RING E3 Biology through Proteomics-based Substrate Identification
J. Wade Harper et al.
MOLECULAR & CELLULAR PROTEOMICS (2012)
BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs
Rebecca Mathew et al.
NATURE (2012)
Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities
Lynn M. Boyden et al.
NATURE (2012)
Comprehensive genomic characterization of squamous cell lung cancers
Peter S. Hammerman et al.
NATURE (2012)
Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma
Guangwu Guo et al.
NATURE GENETICS (2012)
Lack of Cul4b, an E3 Ubiquitin Ligase Component, Leads to Embryonic Lethality and Abnormal Placental Development
Baichun Jiang et al.
PLOS ONE (2012)
The Amelioration of Renal Damage in Skp2-Deficient Mice Canceled by p27 Kip1 Deficiency in Skp2-/- p27-/- Mice
Sayuri Suzuki et al.
PLOS ONE (2012)
SCF ubiquitin ligases in the maintenance of genome stability
Joshua S. Silverman et al.
TRENDS IN BIOCHEMICAL SCIENCES (2012)
Targeting Cullin-RING ligases by MLN4924 induces autophagy via modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axis
Y. Zhao et al.
CELL DEATH & DISEASE (2012)
F-Box Only Protein 7 Gene in Parkinsonian-Pyramidal Disease
Hao Deng et al.
JAMA Neurology (2012)
Skp2 Is Necessary for Myc-Induced Keratinocyte Proliferation but Dispensable for Myc Oncogenic Activity in the Oral Epithelium
Christopher Sistrunk et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
The role of Skp2 in hematopoietic stem cell quiescence, pool size, and self-renewal
Jing Wang et al.
BLOOD (2011)
A Cullin3-KLHL20 Ubiquitin Ligase-Dependent Pathway Targets PML to Potentiate HIF-1 Signaling and Prostate Cancer Progression
Wei-Chien Yuan et al.
CANCER CELL (2011)
Inhibition of NEDD8-Activating Enzyme Induces Rereplication and Apoptosis in Human Tumor Cells Consistent with Deregulating CDT1 Turnover
Michael A. Milhollen et al.
CANCER RESEARCH (2011)
The FBXL5-IRP2 Axis Is Integral to Control of Iron Metabolism In Vivo
Toshiro Moroishi et al.
CELL METABOLISM (2011)
Maternal uniparental isodisomy and heterodisomy on chromosome 6 encompassing a CUL7 gene mutation causing 3M syndrome
K. Sasaki et al.
CLINICAL GENETICS (2011)
SCF E3 Ubiquitin Ligases as Anticancer Targets
L. Jia et al.
CURRENT CANCER DRUG TARGETS (2011)
Cul4A is essential for spermatogenesis and male fertility
Dragana Kopanja et al.
DEVELOPMENTAL BIOLOGY (2011)
The E3 ubiquitin ligase Cullin 4A regulates meiotic progression in mouse spermatogenesis
Yan Yin et al.
DEVELOPMENTAL BIOLOGY (2011)
SAG/RBX2/ROC2 E3 Ubiquitin Ligase Is Essential for Vascular and Neural Development by Targeting NF1 for Degradation
Mingjia Tan et al.
DEVELOPMENTAL CELL (2011)
Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution
Keiko Taguchi et al.
GENES TO CELLS (2011)
Transgenic Mice for Cre-Inducible Overexpression of the Cul4A Gene
Tong Li et al.
GENESIS (2011)
Impaired ovarian development and reduced fertility in female mice deficient in Skp2
Abbas Fotovati et al.
JOURNAL OF ANATOMY (2011)
RBX1 (RING Box Protein 1) E3 Ubiquitin Ligase Is Required for Genomic Integrity by Modulating DNA Replication Licensing Proteins
Lijun Jia et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Fbxw7-dependent Degradation of Notch Is Required for Control of Stemness and Neuronal-Glial Differentiation in Neural Stem Cells
Akinobu Matsumoto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Knockdown of Fbxo7 reveals its regulatory role in proliferation and differentiation of haematopoietic precursor cells
El Kahina Meziane et al.
JOURNAL OF CELL SCIENCE (2011)
Fbxw7 regulates lipid metabolism and cell fate decisions in the mouse liver
Ichiro Onoyama et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
The Fbx4 Tumor Suppressor Regulates Cyclin D1 Accumulation and Prevents Neoplastic Transformation
Laura Pontano Vaites et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction
Hiroyuki Inuzuka et al.
NATURE (2011)
Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7
Ingrid E. Wertz et al.
NATURE (2011)
Inactivation of SAG E3 Ubiquitin Ligase Blocks Embryonic Stem Cell Differentiation and Sensitizes Leukemia Cells to Retinoid Acid
Mingjia Tan et al.
PLOS ONE (2011)
The cullin protein family
Antonio Sarikas et al.
GENOME BIOLOGY (2011)
Induction of p21-Dependent Senescence by an NAE Inhibitor, MLN4924, as a Mechanism of Growth Suppression
Lijun Jia et al.
NEOPLASIA (2011)
RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis
Stanley Lipkowitz et al.
NATURE REVIEWS CANCER (2011)
SCFFbx2-E3-ligase-mediated degradation of BACE1 attenuates Alzheimer's disease amyloidosis and improves synaptic function
Bing Gong et al.
AGING CELL (2010)
Ubiquitin ligase complexes: from substrate selectivity to conjugational specificity
Vanja Nagy et al.
BIOLOGICAL CHEMISTRY (2010)
MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: rationale for treatment of NF-κB-dependent lymphoma
Michael A. Milhollen et al.
BLOOD (2010)
Inhibition of NEDD8-activating enzyme: a novel approach for the treatment of acute myeloid leukemia
Ronan T. Swords et al.
BLOOD (2010)
NEDD8-Targeting Drug MLN4924 Elicits DNA Rereplication by Stabilizing Cdt1 in S Phase, Triggering Checkpoint Activation, Apoptosis, and Senescence in Cancer Cells
Jie Jessie Lin et al.
CANCER RESEARCH (2010)
Validation of SAG/RBX2/ROC2 E3 Ubiquitin Ligase as an Anticancer and Radiosensitizing Target
Lijun Jia et al.
CLINICAL CANCER RESEARCH (2010)
Disruption of Sag/Rbx2/Roc2 induces radiosensitization by increasing ROS levels and blocking NF-κB activation in mouse embryonic stem cells
Mingjia Tan et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
F-box and WD Repeat Domain-Containing 7 Regulates Intestinal Cell Lineage Commitment and Is a Haploinsufficient Tumor Suppressor
Rocio Sancho et al.
GASTROENTEROLOGY (2010)
Spermatogenesis rescue in a mouse deficient for the ubiquitin ligase SCFβ-TrCP by single substrate depletion
Naama Kanarek et al.
GENES & DEVELOPMENT (2010)
The cyclin E regulator cullin 3 prevents mouse hepatic progenitor cells from becoming tumor-initiating cells
Uta Kossatz et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Skp2 Directs Myc-Mediated Suppression of p27(Kip1) yet Has Modest Effects on Myc-Driven Lymphomagenesis
Jennifer B. Old et al.
MOLECULAR CANCER RESEARCH (2010)
Substrate-Assisted Inhibition of Ubiquitin-like Protein-Activating Enzymes: The NEDD8 E1 Inhibitor MLN4924 Forms a NEDD8-AMP Mimetic In Situ
James E. Brownell et al.
MOLECULAR CELL (2010)
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence
Hui-Kuan Lin et al.
NATURE (2010)
Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1(+/-) mice
Hongbo Wang et al.
NATURE GENETICS (2010)
Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun
Joerg D. Hoeck et al.
NATURE NEUROSCIENCE (2010)
Ubiquitin signalling in DNA replication and repair
Helle D. Ulrich et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Cul1 expression is increased in early stages of human melanoma
Guangdi Chen et al.
PIGMENT CELL & MELANOMA RESEARCH (2010)
The Role of Ubiquitin in NF-kappa B Regulatory Pathways
Brian Skaug et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2009)
RING Domain E3 Ubiquitin Ligases
Raymond J. Deshaies et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2009)
Mutational analysis of hypoxia-related genes HIF1α and CUL2 in common human cancers
Sang Wook Park et al.
APMIS (2009)
Identification of a conserved F-box protein 6 interactor essential for endocytosis and cytokinesis in fission yeast
Isabelle Jourdain et al.
BIOCHEMICAL JOURNAL (2009)
ROC1/RBX1 E3 Ubiquitin Ligase Silencing Suppresses Tumor Cell Growth via Sequential Induction of G2-M Arrest, Apoptosis, and Senescence
Lijun Jia et al.
CANCER RESEARCH (2009)
SnapShot: F Box Proteins I
Jeffrey R. Skaar et al.
CELL (2009)
Restriction of Src Activity by Cullin-5
George S. Laszlo et al.
CURRENT BIOLOGY (2009)
Abnormal Retinal Development in the Btrc Null Mouse
Mark Baguma-Nibasheka et al.
DEVELOPMENTAL DYNAMICS (2009)
Ubiquitin in trafficking: The network at work
Filippo Acconcia et al.
EXPERIMENTAL CELL RESEARCH (2009)
S-phase kinase-associated protein-2 (Skp2) promotes vascular smooth muscle cell proliferation and neointima formation in vivo
Yih-Jer Wu et al.
JOURNAL OF VASCULAR SURGERY (2009)
Fbxo45 Forms a Novel Ubiquitin Ligase Complex and Is Required for Neuronal Development
Toru Saiga et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Cul3 overexpression depletes Nrf2 in breast cancer and is associated with sensitivity to carcinogens, to oxidative stress, and to chemotherapy
Martin Loignon et al.
MOLECULAR CANCER THERAPEUTICS (2009)
CUL4A Abrogation Augments DNA Damage Response and Protection against Skin Carcinogenesis
Liren Liu et al.
MOLECULAR CELL (2009)
An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer
Teresa A. Soucy et al.
NATURE (2009)
FBXO7 mutations cause autosomal recessive, early-onset parkinsonian-pyramidal syndrome
A. Di Fonzo et al.
NEUROLOGY (2009)
Proliferation defects and genome instability in cells lacking Cul4A
D. Kopanja et al.
ONCOGENE (2009)
The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73
A. Peschiaroli et al.
ONCOGENE (2009)
Modeling sporadic Parkinson's disease by silencing the ubiquitin E3 ligase component, SKP1A
Silvia A. Mandel et al.
PARKINSONISM & RELATED DISORDERS (2009)
RBX1/ROC1 disruption results in early embryonic lethality due to proliferation failure, partially rescued by simultaneous loss of p27
Mingjia Tan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Control of Iron Homeostasis by an Iron-Regulated Ubiquitin Ligase
Ajay A. Vashisht et al.
SCIENCE (2009)
CRL4s: the CUL4-RING E3 ubiquitin ligases
Sarah Jackson et al.
TRENDS IN BIOCHEMICAL SCIENCES (2009)
Absence of SKP2 expression attenuates BCR-ABL-induced myeloproliferative disease
Anupriya Agarwal et al.
BLOOD (2008)
Mutations in Fbx4 inhibit dimerization of the SCFFbx4 ligase and contribute to cyclin D1 overexpression in human cancer
Olena Barbash et al.
CANCER CELL (2008)
SAG/ROC2/RBX2 E3 ligase promotes UVB-induced skin hyperplasia, but not skin tumors, by simultaneously targeting c-Jun/AP-1 and p27
Hongbin He et al.
CARCINOGENESIS (2008)
Structural insights into NEDD8 activation of Cullin-RING ligases: Conformational control of conjugation
David M. Duda et al.
CELL (2008)
Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL
Sahoko Matsuoka et al.
GENES & DEVELOPMENT (2008)
Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7
Benjamin J. Thompson et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Genotoxic Stress-Induced Cyclin D1 Phosphorylation and Proteolysis Are Required for Genomic Stability
Laura L. Pontano et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradation
Xinsong Xu et al.
MOLECULAR CELL (2008)
Diversity of degradation signals in the ubiquitin-proteasome system
Tommer Ravid et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Identification of SCF Ubiquitin Ligase Substrates by Global Protein Stability Profiling
Hsueh-Chi Sherry Yen et al.
SCIENCE (2008)
Deregulated proteolysis by the F-box proteins SKP2 and β-TrCP:: tipping the scales of cancer
David Frescas et al.
NATURE REVIEWS CANCER (2008)
SAG/ROC2/RBX2 is a HIF-1 target gene that promotes HIF-1α ubiquitination and degradation
M. Tan et al.
ONCOGENE (2008)
FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation
Markus Welcker et al.
NATURE REVIEWS CANCER (2008)
Disruption of the Fbxw8 gene results in pre- and postnatal growth retardation in mice
Takeya Tsutsumi et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Clinical, molecular and histopathological features of short stature syndrome with novel CUL7 mutation in Yakuts:: new population isolate in Asia
N. Maksimova et al.
JOURNAL OF MEDICAL GENETICS (2007)
Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis
Ichiro Onoyama et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Altered pattern of Cul-1 protein expression and neddylation in human lung tumours: relationships with CAND I and cyclin E protein levels
C. Salon et al.
JOURNAL OF PATHOLOGY (2007)
SAG/ROC2 E3 ligase regulates skin carcinogenesis by stage-dependent targeting of c-jun/AP1 and IκB-α/NF-κB
Qingyang Gu et al.
JOURNAL OF CELL BIOLOGY (2007)
Renal damage in obstructive nephropathy is decreased in Skp2-deficient mice
Sayuri Suzuki et al.
AMERICAN JOURNAL OF PATHOLOGY (2007)
The F box protein S phase kinase-associated protein 2 regulates adipose mass and adipocyte number in vivo
Paul S. Cooke et al.
OBESITY (2007)
Selective cochlear degeneration in mice lacking the F-box protein, Fbx2, a glycoprotein-specific ubiquitin ligase subunit
Rick F. Nelson et al.
JOURNAL OF NEUROSCIENCE (2007)
Constitutive turnover of cyclin E by Cul3 maintains quiescence
Justina D. McEvoy et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
SAG/ROC2/Rbx2 is a novel activator protein-1 target that promotes c-Jun degradation and inhibits 12-0-tetradecanoylphorbol-13-acetate-induced neoplastic transformation
Qingyang Gu et al.
CANCER RESEARCH (2007)
Mutation in CUL4B, which encodes a member of cullin-RING ubiquitin ligase complex, causes X-linked mental retardation
Yongxin Zou et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2007)
Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, hypogonadism, pes cavus, and tremor
Patrick S. Tarpey et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2007)
Skp2 controls adipocyte proliferation during the development of obesity
Tamon Sakai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
A Critical Role for FBXW8 and MAPK in Cyclin D1 Degradation and Cancer Cell Proliferation
Hiroshi Okabe et al.
PLOS ONE (2006)
Phosphorylation-dependent ubiquitination of cyclin D1 by the SCFFBX4-αB crystallin complex
Douglas I. Lin et al.
MOLECULAR CELL (2006)
Fbxw8 is essential for Cul1-Cul7 complex formation and for placental development
Ryosuke Tsunematsu et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Drug discovery in the ubiquitin-proteasome system
Grzegorz Nalepa et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Ubiquitin ligases: cell-cycle control and cancer
KI Nakayama et al.
NATURE REVIEWS CANCER (2006)
ASB proteins interact with Cullin5 and Rbx2 to form E3 ubiquitin ligase complexes
J Kohroki et al.
FEBS LETTERS (2005)
Multistep skin cancer in mice as a model to study the evolution of cancer cells
CJ Kemp
SEMINARS IN CANCER BIOLOGY (2005)
Identification of mutations in CUL7 in 3-M syndrome
C Huber et al.
NATURE GENETICS (2005)
Dimerization of CUL7 and PARC is not required for all CUL7 functions and mouse development
JR Skaar et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Overexpression of human βTrCP1 deleted of its F box induces tumorigenesis in transgenic mice
N Belaïdouni et al.
ONCOGENE (2005)
Nedd8 on cullin: building an expressway to protein destruction
ZQ Pan et al.
ONCOGENE (2004)
The many faces of β-TrCP E3 ubiquitin ligases:: reflections in the magic mirror of cancer
SY Fuchs et al.
ONCOGENE (2004)
Defective cardiovascular development and elevated cyclin E and notch proteins in mice lacking the Fbw7 F-box protein
MT Tetzlaff et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Mouse Fbw7/Sel-10/Cdc4 is required for Notch degradation during vascular development
R Tsunematsu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Role of F-box protein βTrcp1 in mammary gland development and tumorigenesis
Y Kudo et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
The SCF ubiquitin ligase: Insights into a molecular machine
T Cardozo et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases
T Kamura et al.
GENES & DEVELOPMENT (2004)
Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene
JH Mao et al.
NATURE (2004)
Fbx7 functions in the SCF complex regulating Cdk1-cyclin B-phosphorylated hepatoma up-regulated protein (HURP) proteolysis by a proline-rich region
JM Hsu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
A hitchhiker's guide to the cullin ubiquitin ligases: SCF and its kin
AR Willems et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2004)
Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases
SJ Goldenberg et al.
CELL (2004)
Skp2-dependent degradation of p27kip1 is essential for cell cycle progression
U Kossatz et al.
GENES & DEVELOPMENT (2004)
Systematic analysis and nomenclature of mammalian F-box proteins
JP Jin et al.
GENES & DEVELOPMENT (2004)
Skp2-mediated degradation of p27 regulates progression into mitosis
K Nakayama et al.
DEVELOPMENTAL CELL (2004)
Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis
T Arai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Impaired degradation of inhibitory subunit of NF-κB (IκB) and β-catenin as a result of targeted disruption of the β-TrCP1 gene
K Nakayama et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Control of meiotic and mitotic progression by the F box protein β-Trcp1 in vivo
D Guardavaccaro et al.
DEVELOPMENTAL CELL (2003)
Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development
Y Tokuzawa et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Nedd8-modification of Cul1 is promoted by Roc1 as a Nedd8-E3 ligase and regulates its stability
M Morimoto et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
In vivo interference with Skp1 function leads to genetic instability and neoplastic transformation
R Piva et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
E3 ubiquitin ligase that recognizes sugar chains
Y Yoshida et al.
NATURE (2002)
CUL-4A is critical for early embryonic development
BH Li et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex
N Zheng et al.
NATURE (2002)
SAG/ROC2/Rbx2/Hrt2, a component of SCF E3 ubiquitin ligase:: Genomic structure, a splicing variant, and two family pseudogenes
M Swaroop et al.
DNA AND CELL BIOLOGY (2001)
Skp1p and the F-box protein Rcy1p form a non-SCF complex involved in recycling of the SNARE Snc1p in yeast
JM Galan et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
HIFα targeted for VHL-mediated destruction by proline hydroxylation:: Implications for O2 sensing
M Ivan et al.
SCIENCE (2001)
Targeting of HIF-α to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
P Jaakkola et al.
SCIENCE (2001)
Protein regulation by monoubiquitin
L Hicke
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2001)
Role of the F-box protein Skp2 in lymphomagenesis
E Latres et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
NF1 tumor suppressor gene function: Narrowing the GAP
K Cichowski et al.
CELL (2001)
Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization
K Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Cell cycle-regulated modification of the ribosome by a variant multiubiquitin chain
J Spence et al.
CELL (2000)
Yeast homolog of human SAG/ROC2/Rbx2/Hrt2 is essential for cell growth, but not for germination:: chip profiling implicates its role in cell cycle regulation
M Swaroop et al.
ONCOGENE (2000)
The conserved RING-H2 finger of ROC1 is required for ubiquitin ligation
A Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Targeted disruption of Skp2 results in accumulation of cyclin E and p27Kip1, polyploidy and centrosome overduplication
K Nakayama et al.
EMBO JOURNAL (2000)