4.8 Editorial Material

Insulin-Degrading Enzyme Inhibition, a Novel Therapy for Type 2 Diabetes?

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CELL METABOLISM
卷 20, 期 2, 页码 201-203

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CELL PRESS
DOI: 10.1016/j.cmet.2014.07.016

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  1. NIDDK NIH HHS [R01 DK059579, P30 DK041301] Funding Source: Medline

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The insulin-degrading enzyme (IDE) has been identified as a type 2 diabetes and Alzheimer's disease susceptibility gene, though its physiological function remains unclear. Maianti et al. (2014) now propose that an IDE inhibitor may be a promising therapeutic strategy for type 2 diabetes.

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