期刊
CELL METABOLISM
卷 20, 期 3, 页码 387-389出版社
CELL PRESS
DOI: 10.1016/j.cmet.2014.08.007
关键词
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资金
- Howard Hughes Medical Institute Funding Source: Medline
- NHLBI NIH HHS [P01 HL020948] Funding Source: Medline
Two new studies report that triglyceride (TG)-lowering mutations in APOC3 reduce coronary heart disease (CHD) (Crosby et al., 2014; Jorgensen et al., 2014). Here, we explore limitations of using Mendelian randomization to evaluate CHD risk, including potential confounding by the widespread use of statin therapy.
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