期刊
CELL METABOLISM
卷 17, 期 6, 页码 812-813出版社
CELL PRESS
DOI: 10.1016/j.cmet.2013.05.015
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资金
- NIA NIH HHS [P01 AG034906] Funding Source: Medline
Hormesis is an adaptive stress response implicated in longevity regulation. Schroeder et al. (2013) have now connected stress, epigenetic changes, and aging in yeast by showing that mitochondria-derived reactive oxygen species modulate the chromatin binding capacity of the histone demethylase Rph1p at subtelomeres, resulting in lifespan extension.
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