期刊
CELL METABOLISM
卷 15, 期 3, 页码 292-297出版社
CELL PRESS
DOI: 10.1016/j.cmet.2012.02.004
关键词
-
资金
- Terry Fox Research Institute [TFF-116128]
Leptin plays a central role in weight control by suppressing food intake and increasing energy expenditure. The concept of leptin resistance emerged to explain the seemingly paradoxical elevated leptin levels in obesity. Recent discoveries reveal that protein tyrosine phosphatases are key players in leptin resistance by globally suppressing leptin signaling.
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