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Power Surge: Supporting Cells Fuel Cancer Cell Mitochondria

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CELL METABOLISM
卷 15, 期 1, 页码 4-5

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CELL PRESS
DOI: 10.1016/j.cmet.2011.12.011

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An emerging paradigm in tumor metabolism is that catabolism in host cells fuels the anabolic growth of cancer cells via energy transfer. A study in Nature Medicine (Nieman et al., 2011) supports this; they show that triglyceride catabolism in adipocytes drives ovarian cancer metastasis by providing fatty acids as mitochondrial fuels.

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