期刊
BRITISH MEDICAL BULLETIN
卷 66, 期 -, 页码 255-265出版社
OXFORD UNIV PRESS
DOI: 10.1093/bmb/66.1.255
关键词
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Human prion diseases can be classified as sporadic, hereditary or acquired. The cause of sporadic Creutzfeldt-Jakob disease (CJD) is unknown, hereditary cases are associated with mutations of the prion protein gene (PRNP) and acquired forms are caused by the transmission of infection from human to human or, as a zoonosis, from cattle to human. Although acquired forms of human prion disease are rare, the transmission of a fatal and untreatable neurological disorder has had major implications for public health and public policy.
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