期刊
INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM
卷 13, 期 4, 页码 436-453出版社
HUMAN KINETICS PUBL INC
DOI: 10.1123/ijsnem.13.4.436
关键词
exercise immunology; glucose ingestion; cycling exercise
The purpose of the present study was to examine the. effect of pre-exercise carbohydrate (CHO) ingestion on circulating leukocyte numbers,. plasma interleukin (IL)-6, plasma cortisol, and lipopolysaccharide (LPS)-stimulated neutrophil degramilation responses in moderately trained male cyclists who completed approximately 1-h of high-intensity cycling. The influence of the timing of pm-exercise CHO ingestion was investigated in 8 subjects who consumed,75 g CHO as a glucose solution at either 15 (-15 trial), or 75 (-75 trial) min before the onset of exercise. The influence of the amount of pre-exercise CHO ingestion was investigated in a further 10 subjects who consumed either 25 g or 200 g CHO as a glucose solution or a placebo 45 min before the onset of exercise. At the onset of exercise in the timing experiment, the plasma glucose concentration was significantly (p <.05) lower on the -75 trial compared with pre-drink values, and the plasma cortisol concentration and neutrophil to lymphocyte (N/L) ratio were significantly (p <.05) elevated in the post-exercise period. In the -15 trial, plasma glucose concentration was well maintained, and the plasma cortisol. concentration and N/L ratio were not significantly elevated above resting levels. However, LPS-stimulated neutrophil degranulation was similar in the-15 and -75 trials. The amount of CHO ingested had no effect on the magnitude of the rise in the N/L ratio compared-with placebo when consumed 45 min pre-exercise. Finally, although an exercise-induced increase in the plasma IL-6 concentration was observed, this effect was independent of pre-exercise CHO ingestion.
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