期刊
CELL HOST & MICROBE
卷 8, 期 1, 页码 12-15出版社
CELL PRESS
DOI: 10.1016/j.chom.2010.06.009
关键词
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资金
- National Institutes of Health
- United States Department of Agriculture
RNA-based viral immunity (RVI) operates in fungi, plants, and invertebrates to specifically destroy viral RNAs using the cellular RNA interference machinery. Discovery of diverse viral proteins as suppressors of RNA silencing provides strong validation for the effectiveness of RVI. Here we review recent studies that have revealed new mechanistic insights into plant and insect viral suppressors of RVI or suggested a role for RNA silencing suppression during mammalian viral infection.
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