相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Smac Modulates Chemosensitivity in Head and Neck Cancer Cells through the Mitochondrial Apoptotic Pathway
Quanhong Sun et al.
CLINICAL CANCER RESEARCH (2011)
Delayed-Onset Caspase-Dependent Massive Hepatocyte Apoptosis upon Fas Activation in Bak/Bax-Deficient Mice
Hayato Hikita et al.
HEPATOLOGY (2011)
Non-apoptotic role of BID in inflammation and innate immunity
Garabet Yeretssian et al.
NATURE (2011)
Smac Mimetic Increases Chemotherapy Response and Improves Survival in Mice with Pancreatic Cancer
Sean P. Dineen et al.
CANCER RESEARCH (2010)
XIAP as a ubiquitin ligase in cellular signaling
S. Galban et al.
CELL DEATH AND DIFFERENTIATION (2010)
MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria
Yehudit Zaltsman et al.
NATURE CELL BIOLOGY (2010)
New insights into apoptosis signaling by Apo2L/TRAIL
F. Gonzalvez et al.
ONCOGENE (2010)
IAPs: from caspase inhibitors to modulators of NF-κB, inflammation and cancer
Mads Gyrd-Hansen et al.
NATURE REVIEWS CANCER (2010)
Cytoprotective effects of IAPs revealed by a small molecule antagonist
Stefanie Galban et al.
BIOCHEMICAL JOURNAL (2009)
A Smac-mimetic sensitizes prostate cancer cells to TRAIL-induced apoptosis via modulating both IAPs and NF-kappaB
Yao Dai et al.
BMC CANCER (2009)
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009
G. Kroemer et al.
CELL DEATH AND DIFFERENTIATION (2009)
The Strength of the Fas Ligand Signal Determines Whether Hepatocytes Act as Type 1 or Type 2 Cells in Murine Livers
Sven Schuengel et al.
HEPATOLOGY (2009)
Fatal Hepatitis Mediated by Tumor Necrosis Factor TNFα Requires Caspase-8 and Involves the BH3-Only Proteins Bid and Bim
Thomas Kaufmann et al.
IMMUNITY (2009)
The Many Roles of FAS Receptor Signaling in the Immune System
Andreas Strasser et al.
IMMUNITY (2009)
X Chromosome-linked Inhibitor of Apoptosis Regulates Cell Death Induction by Proapoptotic Receptor Agonists
Eugene Varfolomeev et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment
Peter Geserick et al.
JOURNAL OF CELL BIOLOGY (2009)
XIAP discriminates between type I and type II FAS-induced apoptosis
Philipp J. Jost et al.
NATURE (2009)
Membrane-bound Fas ligand only is essential for Fas-induced apoptosis
Lorraine A. O' Reilly et al.
NATURE (2009)
Combined inhibition of FLIP and XIAP induces Bax-independent apoptosis in type II colorectal cancer cells
T. R. Wilson et al.
ONCOGENE (2009)
Mutational analyses of c-FLIPR, the only murine short FLIP isoform, reveal requirements for DISC recruitment
N. Ueffing et al.
CELL DEATH AND DIFFERENTIATION (2008)
In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute
E. M. Michalak et al.
CELL DEATH AND DIFFERENTIATION (2008)
Regulation of apoptosis by XIAP ubiquitin-ligase activity
Andrew J. Schile et al.
GENES & DEVELOPMENT (2008)
The BCL-2 protein family: opposing activities that mediate cell death
Richard J. Youle et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?
Jerry E. Chipuk et al.
TRENDS IN CELL BIOLOGY (2008)
IAP antagonists induce autoubiquitination of c-IAPs, NF-κB activation, and TNFα-dependent apoptosis
Eugene Varfolomeev et al.
CELL (2007)
IAP antagonists target cIAP1 to induce TNFα- dependent apoptosis
James E. Vince et al.
CELL (2007)
ER stress triggers apoptosis by activating BH3-only protein Bim
Hamsa Puthalakath et al.
CELL (2007)
XIAP induces NF-κB activation via the BIR1/TAB1 interaction and BIR1 dimerization
Miao Lu et al.
MOLECULAR CELL (2007)
The CD95 receptor: Apoptosis revisited
Marcus E. Peter et al.
CELL (2007)
The BH3-only protein bid is dispensable for DNA darnage- and replicative stress-induced apoptosis or cell-cycle arrest
Thomas Kaufmann et al.
CELL (2007)
Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak
Simon N. Willis et al.
SCIENCE (2007)
p53 in health and disease
Karen H. Vousden et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
The inhibitors of apoptosis (IAPs) as cancer targets
Allison M. Hunter et al.
APOPTOSIS (2007)
Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family
Brendan P. Eckelman et al.
EMBO REPORTS (2006)
Specific ablation of the apoptotic functions of cytochrome c reveals a differential requirement for cytochrome c and apaf-1 in apoptosis
ZY Hao et al.
CELL (2005)
BH3 domains of BH3-only proteins differentially regulate bax-mediated mitochondrial membrane permeabilization both directly and indirectly
T Kuwana et al.
MOLECULAR CELL (2005)
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
L Chen et al.
MOLECULAR CELL (2005)
XIAP-deficiency leads to delayed lobuloalveolar development in the mammary gland
MA Olayioye et al.
CELL DEATH AND DIFFERENTIATION (2005)
Differential signaling to apoptotic and necrotic cell death by Fas-associated death domain protein FADD
T Vanden Berghe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of bid by multiple papain-like lysosomal cathepsins
T Cirman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
p53- and drug-induced apoptotic responses mediated by BH3-only proteins Puma and Noxa
A Villunger et al.
SCIENCE (2003)
Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells
A Enders et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Puma is an essential mediator of p53-dependent and -independent apoptotic pathways
JR Jeffers et al.
CANCER CELL (2003)
Integral role of Noxa in p53-mediated apoptotic response
T Shibue et al.
GENES & DEVELOPMENT (2003)
Signalling pathways of the TNF superfamily: A double-edged sword
BB Aggarwal
NATURE REVIEWS IMMUNOLOGY (2003)
BID-D59A is a potent inducer of apoptosis in primary embryonic fibroblasts
R Sarig et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
A unified model for apical caspase activation
KM Boatright et al.
MOLECULAR CELL (2003)
Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex
N Holler et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
A Letai et al.
CANCER CELL (2002)
Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1
HD Ryoo et al.
NATURE CELL BIOLOGY (2002)
Targeting death and decoy receptors of the tumour-necrosis factor superfamily
A Ashkenazi
NATURE REVIEWS CANCER (2002)
Keeping killers on a tight leash: transcriptional and posttranslational control of the pro-apoptotic activity of BH3-only proteins
H Puthalakath et al.
CELL DEATH AND DIFFERENTIATION (2002)
Calpain-mediated bid cleavage and calpain-independent Bak modulation: Two separate pathways in cisplatin-induced apoptosis
A Mandic et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression
S Fulda et al.
ONCOGENE (2002)
BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes
P Bouillet et al.
NATURE (2002)
Identification of Omi/HtrA-2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction
R Hegde et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
TRAIL-induced apoptosis requires Bax-dependent mitochondria release of Smac/DIABLO
YB Deng et al.
GENES & DEVELOPMENT (2002)
Molecular ordering of the initial signaling events of CD95
A Algeciras-Schimnich et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death
Y Suzuki et al.
MOLECULAR CELL (2001)
BCL-2, BCL-XL sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis
EHYA Cheng et al.
MOLECULAR CELL (2001)
Bid is cleaved by calpain to an active fragment in vitro and during myocardial ischemia/reperfusion
M Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Activation of pro-death Bcl-2 family proteins and mitochondria apoptosis pathway in tumor necrosis factor-α-induced liver injury
YG Zhao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP
J Silke et al.
EMBO JOURNAL (2001)
BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
WX Zong et al.
GENES & DEVELOPMENT (2001)
Characterization of XIAP-deficient mice
H Harlin et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
MC Wei et al.
SCIENCE (2001)
Thymocyte-targeted overexpression of xiap transgene disrupts T lymphoid apoptosis and maturation
D Conte et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Structural basis for the inhibition of caspase-3 by XIAP
SJ Riedl et al.
CELL (2001)
PUMA induces the rapid apoptosis of colorectal cancer cells
J Yu et al.
MOLECULAR CELL (2001)
PUMA, a novel proapoptotic gene, is induced by p53
K Nakano et al.
MOLECULAR CELL (2001)
BH3-Only proteins - Essential initiators of apoptotic cell death
DCS Huang et al.
CELL (2000)
The combined functions of proapoptotic Bcl-2 family members Bak and Bax are essential for normal development of multiple tissues
T Lindsten et al.
MOLECULAR CELL (2000)
TCR-mediated up-regulation of c-FLIPshort correlates with resistance toward CD95-mediated apoptosis by blocking death-inducing signaling complex activity
S Kirchhoff et al.
JOURNAL OF IMMUNOLOGY (2000)
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule
N Holler et al.
NATURE IMMUNOLOGY (2000)
Initiation of apoptosis by granzyme B requires direct cleavage of Bid, but not direct granzyme B-mediated caspase activation
VR Sutton et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Bcl-XL protects pancreatic adenocarcinoma cells against CD95-and TRAIL-receptor-mediated apoptosis
S Hinz et al.
ONCOGENE (2000)
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
CY Du et al.
CELL (2000)
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
AM Verhagen et al.
CELL (2000)
Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations
RM Siegel et al.
SCIENCE (2000)
Nora, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
E Oda et al.
SCIENCE (2000)
Opposing effects of transmembrane and soluble Fas ligand expression on inflammation and tumor cell survival
AM Hohlbaum et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)