4.7 Review

Caspases and cancer

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Christopher A. Haiman et al.

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TAp73β and DNp73β activate the expression of the pro-survival caspase-2S

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A common coding variant in CASP8 is associated with breast cancer risk

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Are promyelocytic leukaemia protein nuclear bodies a scaffold for caspase-2 programmed cell death?

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Caspase 8 is absent or low in many ex vivo gliomas

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Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease

PM Horowitz et al.

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Cell division and cell survival in the absence of survivin

D Yang et al.

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The C terminus of c-Src inhibits breast tumor cell growth by a kinase-independent mechanism

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JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

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Inactivating mutations of CASPASE-7 gene in human cancers

YH Soung et al.

ONCOGENE (2003)

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Inactivating mutations of caspase-8 gene in colorectal carcinomas

HS Kim et al.

GASTROENTEROLOGY (2003)

Article Immunology

Caspase-8 and caspase-10 activate NF-κB through RIP, NIK and IKKα kinases

Y Shikama et al.

EUROPEAN JOURNAL OF IMMUNOLOGY (2003)

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A unified model for apical caspase activation

KM Boatright et al.

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Down-regulation of caspase 3 in breast cancer: a possible mechanism for chemoresistance

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ONCOGENE (2002)

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Inactivating mutations of the caspase-10 gene in gastric cancer

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Death effector domain-only polypeptides of caspase-8 and-10 specifically inhibit death receptor-induced cell death

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Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8.

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Caspase-10 is an initiator caspase in death receptor signaling

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Molecular cloning and characterization of a novel caspase-3 variant that attenuates apoptosis induced by proteasome inhibition

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Executioner caspase-3,-6, and-7 perform distinct, non-redundant roles during the demolition phase of apoptosis

EA Slee et al.

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Identification of XAF1 as an antagonist of XIAP anti-caspase activity

P Liston et al.

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Caspase-2 pre-mRNA alternative splicing:: Identification of an intronic element containing a decoy 3′ acceptor site

J Côté et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

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Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation

TS Zheng et al.

NATURE MEDICINE (2000)

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Activation of the NF-κB pathway by Caspase 8 and its homologs

PM Chaudhary et al.

ONCOGENE (2000)

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Activation of NF-κB by FADD, Casper, and caspase-8

WH Hu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)