Bioactive triterpenoids from Symplocos chinensis

A new triterpenoid, 2beta,3beta,19alpha,24-tetrahydroxy-23-norurs-12-en-28-oic acid ( 4 ), together with three known triterpenoids 3-oxo-19alpha,23,24-trihydroxyurs-12-en-28-oic acid ( 1 ), 2alpha,3beta,19alpha,23-tetrahydroxyurs-12-en-28-oic acid ( 2 ), 2alpha,3alpha,19alpha,23-tetrahydroxyurs-12-en-28-oic acid ( 3 ), was isolated from the roots of Symplocos chinensis . The new triterpenoid shows significant cytotoxic activity against B16 and BGC-823 cells.