相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Mcl1 downregulation sensitizes neuroblastoma to cytotoxic chemotherapy and small molecule Bcl2-family antagonists
Brian J. Lestini et al.
CANCER BIOLOGY & THERAPY (2009)
Different forms of cell death induced by putative BCL2 inhibitors
M. Vogler et al.
CELL DEATH AND DIFFERENTIATION (2009)
BAX activation is initiated at a novel interaction site
Evripidis Gavathiotis et al.
NATURE (2008)
Identification of ALK as a major familial neuroblastoma predisposition gene
Yael P. Mosse et al.
NATURE (2008)
Initial testing (stage 1) of the BH3 mimetic ABT-263 by the pediatric preclinical testing program
Richard Lock et al.
PEDIATRIC BLOOD & CANCER (2008)
Activation of the JNK pathway promotes phosphorylation and degradation of BimEL -: a novel mechanism of chemoresistance in T-cell acute lymphoblastic leukemia
Kam Tong Leung et al.
CARCINOGENESIS (2008)
BCL-2 dependence and ABT-737 sensitivity in acute lymphoblastic leukemia
Victoria Del Gaizo Moore et al.
BLOOD (2008)
Diagnosing and exploiting cancer's addiction to blocks in apoptosis
Anthony G. Letai
NATURE REVIEWS CANCER (2008)
Crosstalk among Bcl-2 family members in B-CLL: seliciclib acts via the Mcl-1/Noxa axis and gradual exhaustion of Bcl-2 protection
D. Y. H. Hallaert et al.
CELL DEATH AND DIFFERENTIATION (2007)
BH3 profiling identifies three distinct classes of apoptotic blocks to predict response to ABT-737 and conventional chemotherapeutic agents
Jing Deng et al.
CANCER CELL (2007)
Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak
Rachel T. Uren et al.
JOURNAL OF CELL BIOLOGY (2007)
Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak
Simon N. Willis et al.
SCIENCE (2007)
Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing bak activation and bax translocation
Shuang Chen et al.
CANCER RESEARCH (2007)
Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737
Victoria Del Gaizo Moore et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies
Hyungjin Kim et al.
NATURE CELL BIOLOGY (2006)
The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized
Mark F. van Delft et al.
CANCER CELL (2006)
Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia
Marina Konopleva et al.
CANCER CELL (2006)
BH3 peptidomimetics potently activate apoptosis and demonstrate single agent efficacy in neuroblastoma
K. C. Goldsmith et al.
ONCOGENE (2006)
BCL-2 in the crosshairs: tipping the balance of life and death
L. D. Walensky
CELL DEATH AND DIFFERENTIATION (2006)
Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members
Michael Certo et al.
CANCER CELL (2006)
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
T Oltersdorf et al.
NATURE (2005)
Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins
SN Willis et al.
GENES & DEVELOPMENT (2005)
BH3 domains of BH3-only proteins differentially regulate bax-mediated mitochondrial membrane permeabilization both directly and indirectly
T Kuwana et al.
MOLECULAR CELL (2005)
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
L Chen et al.
MOLECULAR CELL (2005)
Application of real-time cell electronic sensing (RT-CES) technology to cell-based assays
K Solly et al.
ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2004)
The requirement for evasion of programmed cell death in neuroblastomas with MYCN amplification
MD Hogarty
CANCER LETTERS (2003)
Minimal BH3 peptides promote cell death by antagonizing anti-apoptotic proteins
C Moreau et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
A Letai et al.
CANCER CELL (2002)
Bmf: A proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis
H Puthalakath et al.
SCIENCE (2001)
Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells
JL Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)