相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。HIF-dependent antitumorigenic effect of antioxidants in vivo
Ping Gao et al.
CANCER CELL (2007)
The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production
Eric L. Bell et al.
JOURNAL OF CELL BIOLOGY (2007)
HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells
Ryo Fukuda et al.
CELL (2007)
Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro
Yi Pan et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
I Papandreou et al.
CELL METABOLISM (2006)
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
JW Kim et al.
CELL METABOLISM (2006)
Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-α activation
KD Mansfield et al.
CELL METABOLISM (2005)
Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing
RD Guzy et al.
CELL METABOLISM (2005)
Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation
JK Brunelle et al.
CELL METABOLISM (2005)
JunD reduces tumor angiogenesis by protecting cells from oxidative stress
D Gerald et al.
CELL (2004)
Complex III releases superoxide to both sides of the inner mitochondrial membrane
FL Muller et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Mutation in mitochondrial complex I ND6 subunit is associated with defective response to hypoxia in human glioma cells
Carrie DeHaan et al.
MOLECULAR CANCER (2004)
Redistribution of intracellular oxygen in hypoxia by nitric oxide:: Effect on HIF1α
T Hagen et al.
SCIENCE (2003)
Differential roles of hypoxia-inducible factor 1α (HIF-1α) and HIF-2α in hypoxic gene regulation
CJ Hu et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Mitochondrial formation of reactive oxygen species
JF Turrens
JOURNAL OF PHYSIOLOGY-LONDON (2003)
Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor
M Hirsilä et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Essential role of complex II of the respiratory chain in hypoxia-induced ROS generation in the pulmonary vasculature
R Paddenberg et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2003)
Hypoxic but not anoxic stabilization of HIF-1α requires mitochondrial reactive oxygen species
C Schroedl et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2002)
Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor
M Ivan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor
D Lando et al.
GENES & DEVELOPMENT (2002)
Structural basis for Hif-1α/CBP recognition in the cellular hypoxic response
SA Dames et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1α
SJ Freedman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
The contribution of VHL substrate binding and HIF1-α to the phenotype of VHL loss in renal cell carcinoma
JK Maranchie et al.
CANCER CELL (2002)
Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein
K Kondo et al.
CANCER CELL (2002)
Asparagine hydroxylation of the HIF transactivation domain: A hypoxic switch
D Lando et al.
SCIENCE (2002)
Bcl-2 family members and functional electron transport chain regulate oxygen deprivation-induced cell death
DS McClintock et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
A conserved family of prolyl-4-hydroxylases that modify HIF
RK Bruick et al.
SCIENCE (2001)
FIH-1:: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity
PC Mahon et al.
GENES & DEVELOPMENT (2001)
C-elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
ACR Epstein et al.
CELL (2001)
The site of production of superoxide radical in mitochondrial Complex I is not a bound ubisemiquinone but presumably iron-sulfur cluster N2
ML Genova et al.
FEBS LETTERS (2001)
Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain
EC Vaux et al.
BLOOD (2001)
HIFα targeted for VHL-mediated destruction by proline hydroxylation:: Implications for O2 sensing
M Ivan et al.
SCIENCE (2001)
Targeting of HIF-α to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
P Jaakkola et al.
SCIENCE (2001)
The role of mitochondria in the regulation of hypoxia-inducible factor 1 expression during hypoxia
FH Agani et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1α during hypoxia -: A mechanism of O2 sensing
NS Chandel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Redox regulation of p53 during hypoxia
NS Chandel et al.
ONCOGENE (2000)
The expression and distribution of the hypoxia-inducible factors HIF-1α and HIF-2α in normal human tissues, cancers, and tumor-associated macrophages
KL Talks et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
分享论文
