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Delin Chen et al.
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Georgia Velimezi et al.
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Ana Rita Carlos et al.
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Yusuke Higashi et al.
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Insulin-like growth factor-1 receptor activation prevents hydrogen peroxide-induced oxidative stress, mitochondrial dysfunction and apoptosis
Chang-Ning Hao et al.
APOPTOSIS (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
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Maria Sideridou et al.
JOURNAL OF CELL BIOLOGY (2011)
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Kevin M. Haigis et al.
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The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression
Daniel Schramek et al.
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Transcription-independent ARF regulation in oncogenic stress-mediated p53 responses
Delin Chen et al.
NATURE (2010)
Genomic instability - an evolving hallmark of cancer
Simona Negrini et al.
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WIP1 phosphatase at the crossroads of cancer and aging
Xavier Le Guezennec et al.
TRENDS IN BIOCHEMICAL SCIENCES (2010)
Tied Up in Loops: Positive and Negative Autoregulation of p53
Xin Lu
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)
Modes of p53 Regulation
Jan-Philipp Kruse et al.
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Stephen P. Jackson et al.
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Erwin F. Wagner et al.
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The type 2C phosphatase Wip1: An oncogenic regulator of tumor suppressor and DNA damage response pathways
Xiongbin Lu et al.
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Distinct Thresholds Govern Myc's Biological Output In Vivo
Daniel J. Murphy et al.
CANCER CELL (2008)
ROS and p53: A versatile partnership
Bin Liu et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
A novel ATM-Dependent pathway regulates protein phosphatase 1 in response to DNA damage
Xi Tang et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
An oncogene-induced DNA damage model for cancer development
Thanos D. Halazonetis et al.
SCIENCE (2008)
A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D
S. Rayter et al.
ONCOGENE (2008)
Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage
Bin Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Deregulated overexpression of hCdtl and hCdc6 promotes malignant Behavior
Michalis Liontos et al.
CANCER RESEARCH (2007)
Glutathione S-transferase-P1 expression correlates with increased antioxidant capacity in transitional cell carcinoma of the urinary bladder
Ana Savic-Radojevic et al.
EUROPEAN UROLOGY (2007)
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
Shuhei Matsuoka et al.
SCIENCE (2007)
JNK pathway: diseases and therapeutic potential
Jie Cui et al.
ACTA PHARMACOLOGICA SINICA (2007)
DNA damage checkpoints: from initiation to recovery or adaptation
Jiri Bartek et al.
CURRENT OPINION IN CELL BIOLOGY (2007)
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H. F. Horn et al.
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p38α MAP kinase as a sensor of reactive oxygen species in tumorigenesis
Ignacio Dolado et al.
CANCER CELL (2007)
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
Jirina Bartkova et al.
NATURE (2006)
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
Raffaella Di Micco et al.
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Policing of oncogene activity by p53
Alejo Efeyan et al.
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Wip1 phosphatase modulates ATM-dependent signaling pathways
Sathyavageeswaran Shreeram et al.
MOLECULAR CELL (2006)
p14ARF activates a Tip60-dependent and p53-independent ATM/ATR/CHK pathway in response to genotoxic stress
Beatrice Eymin et al.
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被撤回的出版物: Oncogenic activity of Cdc6 through repression of the INK4/ARF locus (Retracted article. See vol. 547, pg. 246, 2017)
S Gonzalez et al.
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B23 and ARF - Friends or foes?
Mikael S. Lindstrom et al.
CELL BIOCHEMISTRY AND BIOPHYSICS (2006)
The P53 pathway: what questions remain to be explored?
A. J. Levine et al.
CELL DEATH AND DIFFERENTIATION (2006)
Divorcing ARF and p53: an unsettled case
Charles J. Sherr
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PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints
XB Lu et al.
GENES & DEVELOPMENT (2005)
The p53 pathway: positive and negative feedback loops
SL Harris et al.
ONCOGENE (2005)
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
J Bartkova et al.
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Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
VG Gorgoulis et al.
NATURE (2005)
Regulation of NF-κB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor
S Rocha et al.
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Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16Ink4a-p19Arf pathway
DV Bulavin et al.
NATURE GENETICS (2004)
Physical and functional interactions of the Arf tumor suppressor protein with nucleophosmin/B23
D Bertwistle et al.
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ATM activity contributes to the tumor-suppressing functions of p14ARF
YX Li et al.
ONCOGENE (2004)
Nucleophosmin sets a threshold for p53 response to UV radiation
DA Maiguel et al.
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Nucleolar Arf tumor suppressor inhibits ribosomal RNA processing
M Sugimoto et al.
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Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation
K Itahana et al.
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Osmotic shock induces G1 arrest through p53 phosphorylation at Ser33 by activated p38MAPK without phosphorylation at Ser15 and Ser20
H Kishi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Blocking oncogenic Ras signaling for cancer therapy
AA Adjei
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2001)
MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines
C Tournier et al.
GENES & DEVELOPMENT (2001)
ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage
R Maya et al.
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p53-inducible Wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation
M Takekawa et al.
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Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7
Y Fleming et al.
BIOCHEMICAL JOURNAL (2000)
Rac1 inhibits TNF-α-induced endothelial cell apoptosis:: dual regulation by reactive oxygen species
SS Deshpande et al.
FASEB JOURNAL (2000)
An N-terminal p14ARF peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivo
CA Midgley et al.
ONCOGENE (2000)