相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。The anti-diabetic drug metformin suppresses self-renewal and proliferation of trastuzumab-resistant tumor-initiating breast cancer stem cells
Alejandro Vazquez-Martin et al.
BREAST CANCER RESEARCH AND TREATMENT (2011)
A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells
Matthew J. Birket et al.
JOURNAL OF CELL SCIENCE (2011)
Transcriptional evidence for the Reverse Warburg Effect in human breast cancer tumor stroma and metastasis: Similarities with oxidative stress, inflammation, Alzheimer's disease, and Neuron-Glia Metabolic Coupling
Stephanos Pavlides et al.
AGING-US (2010)
Endogenous myoglobin in human breast cancer is a hallmark of luminal cancer phenotype
G. Kristiansen et al.
BRITISH JOURNAL OF CANCER (2010)
Understanding the lethal drivers of tumor-stroma co-evolution Emerging role(s) for hypoxia, oxidative stress and autophagy/mitophagy in the tumor micro-environment
Michael P. Lisanti et al.
CANCER BIOLOGY & THERAPY (2010)
Metformin Prevents Tobacco Carcinogen-Induced Lung Tumorigenesis
Regan M. Memmott et al.
CANCER PREVENTION RESEARCH (2010)
Metformin and Other Biguanides in Oncology: Advancing the Research Agenda
Michael Pollak
CANCER PREVENTION RESEARCH (2010)
The autophagic tumor stroma model of cancer Role of oxidative stress and ketone production in fueling tumor cell metabolism
Stephanos Pavlides et al.
CELL CYCLE (2010)
RB-pathway disruption in breast cancer Differential association with disease subtypes, disease-specific prognosis and therapeutic response
Adam Ertel et al.
CELL CYCLE (2010)
CC3/TIP30 regulates metabolic adaptation of tumor cells to glucose limitation
Vivian Chen et al.
CELL CYCLE (2010)
Ketones and lactate fuel tumor growth and metastasis Evidence that epithelial cancer cells use oxidative mitochondrial metabolism
Gloria Bonuccelli et al.
CELL CYCLE (2010)
The autophagic tumor stroma model of cancer or battery-operated tumor growth A simple solution to the autophagy paradox
Ubaldo E. Martinez-Outschoorn et al.
CELL CYCLE (2010)
Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells
Ubaldo E. Martinez-Outschoorn et al.
CELL CYCLE (2010)
Autophagy in cancer associated fibroblasts promotes tumor cell survival Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment
Ubaldo E. Martinez-Outschoorn et al.
CELL CYCLE (2010)
Loss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the reverse Warburg effect A transcriptional informatics analysis with validation
Stephanos Pavlides et al.
CELL CYCLE (2010)
Tumor cells induce the cancer associated fibroblast phenotype via caveolin-1 degradation Implications for breast cancer and DCIS therapy with autophagy inhibitors
Ubaldo E. Martinez-Outschoorn et al.
CELL CYCLE (2010)
Metformin regulates breast cancer stem cell ontogeny by transcriptional regulation of the epithelial-mesenchymal transition (EMT) status
Alejandro Vazquez-Martin et al.
CELL CYCLE (2010)
Metformin and Energy Metabolism in Breast Cancer: From Insulin Physiology to Tumour-initiating Stem Cells
A. Vazquez-Martin et al.
CURRENT MOLECULAR MEDICINE (2010)
Quantitative mitochondrial redox imaging of breast cancer metastatic potential
He N. Xu et al.
JOURNAL OF BIOMEDICAL OPTICS (2010)
Neurons and Neuronal Stem Cells Survive in Glucose-Free Lactate and in High Glucose Cell Culture Medium During Normoxia and Anoxia
Sascha Wohnsland et al.
NEUROCHEMICAL RESEARCH (2010)
Mapping Dynamic Histone Acetylation Patterns to Gene Expression in Nanog-Depleted Murine Embryonic Stem Cells
Florian Markowetz et al.
PLOS COMPUTATIONAL BIOLOGY (2010)
Role of glutamate in neuron-glia metabolic coupling
Pierre J. Magistretti
AMERICAN JOURNAL OF CLINICAL NUTRITION (2009)
Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission
Heather A. Hirsch et al.
CANCER RESEARCH (2009)
The reverse Warburg effect Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma
Stephanos Pavlides et al.
CELL CYCLE (2009)
[11C] acetoacetate utilization by breast and prostate tumors:: A PET and biodistribution study in mice
Simon Authier et al.
MOLECULAR IMAGING AND BIOLOGY (2008)
Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro
James A. Dykens et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2008)
NCBI GEO: mining tens of millions of expression profiles - database and tools update
Tanya Barrett et al.
NUCLEIC ACIDS RESEARCH (2007)
Neuron-glia metabolic coupling and plasticity
Pierre J. Magistretti
JOURNAL OF EXPERIMENTAL BIOLOGY (2006)
The molecular portraits of breast tumors are conserved across microarray platforms
Zhiyuan Hu et al.
BMC GENOMICS (2006)
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
A Subramanian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature
J Moreaux et al.
BLOOD (2005)
Lactate: Mirror and motor of tumor malignancy
S Walenta et al.
SEMINARS IN RADIATION ONCOLOGY (2004)
Severe lactic acidosis in a 14-year-old female with metastatic undifferentiated carcinoma of unknown primary
JC Cheng et al.
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY (2004)
ArrayExpress - a public repository for microarray gene expression data at the EBI
A Brazma et al.
NUCLEIC ACIDS RESEARCH (2003)
Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer
DM Brizel et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2001)