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Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions
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The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation
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Wg/Wnt signal can be transmitted through Arrow/LRP5,6 and Axin independently of Zw3/Gsk3β activity
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Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of frizzled
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Differential molecular assemblies underlie the dual function of axin in modulating the Wnt and JNK pathways
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