A highly active catalyst system for the heteroarylation of acetone

A highly active catalyst system for the heteroarylation of acetone has been identified. The Coupling between the in situ generated tributyltin enolate of acetone and a variety of heteroaromatic bromides, chlorides, and triflates in the presence of this catalyst system provided arylacetones in good yields. (C) 2003 Elsevier Ltd. All rights reserved.